drugset / Trial / NCT03419559

Study of Autologous Tumor Infiltrating Lymphocytes (LN-145) In Combo With Durvalumab in Non-Small Cell Lung Cancer

NCT03419559 ↗

Phase 2 Withdrawn Iovance Biotherapeutics, Inc.
NaSingle-groupOpen-labelTreatment

Summary

This study is a Phase 2, open-label, multicenter study evaluating adoptive cell therapy (ACT) with autologous TIL therapy (LN-145) in combination with Anti-PD-L1 inhibitor durvalumab.

Timeline

Start
2018-02-28
Primary completion
2021-12
Completion
2024-12

Outcome

Outcome not reported

Stopped: “The treatment landscape for NSCLC has evolved in the past year. An additional NSCLC arm will be added to the IOV-COM-202 study using TIL + pembrolizumab.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Durvalumab Monoclonal antibody — —
Subject Tumor Infiltrating Lymphocytes Cell therapy — —