drugset / Trial / NCT03421652

Nivolumab and RT in Treating Patients With Localized/Locally Advanced Urothelial Bladder Cancer Ineligible for Chemo

NCT03421652 ↗

NaSingle-groupOpen-labelTreatment

Summary

This phase II trial studies how well nivolumab works with radiation therapy in treating patients with urothelial bladder cancer that has spread from its original site of growth to nearby tissues or lymph nodes and are ineligible for chemotherapy. Monoclonal antibodies, such as nivolumab, may interfere with the ability of tumor cells to grow and spread. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Giving nivolumab and radiation therapy may work better in treating patients with urothelial bladder cancer.

Timeline

Start
2018-04-24
Primary completion
2023-03-23
Completion
2023-03-23

Drugs

EvaluationDrugModalityDoseRoute
Subject Nivolumab Monoclonal antibody — Intravenous

Indications