drugset / Trial / NCT03424226

Sickness Evaluation at Altitude With Acetazolamide at Relative Dosages

NCT03424226

Phase 1 Completed 105 enrolled Stanford University
RandomizedParallel-groupQuadruple-blindPrevention

Summary

This double blind randomized trial will compare acetazolamide taken the morning of ascent to acetazolamide taken the evening prior to ascent for the prevention of acute mountain sickness (AMS). The day of ascent dosing has not been studied as a powered primary outcome. The study population is hikers who are ascending at their own rate under their own power in a true hiking environment at the White Mountain Research Station, Owen Valley Lab (OVL) and Bancroft Station (BAR), Bancroft Peak, White Mountain, California

Timeline

Start
2018-08-04
Primary completion
2018-09-30
Completion
2018-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Acetazolamide Small molecule 125 mg