drugset / Trial / NCT03425448

Neutrolin Versus Heparin for Locking Hemodialysis Catheters

NCT03425448

RandomizedSequentialOpen-labelTreatment

Summary

Hemodialysis catheter related bacterial infections represent a major cause of mortality and morbidity in the hemodialysis population. Several locking agents had been tried with variable degree of success but not without side effects. Neutrolin catheter locking agent comprises of heparin,citrate and trauolidine that had been studied in a prospective study in Germany, and it demonstrated a very good result in terms of reducing the catheter related infections and thrombosis. This study is a multi-center, double-blind RCT comparing the hemodialysis catheter locking solution Neutrolin with heparin in reducing the rate of catheter related bacterial infection and thrombosis.

Timeline

Start
2019-04-04
Primary completion
2020-10-04
Completion
2021-04-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Heparin Other / unclassified
Subject Neutrolin Unknown

Indications

No indication recorded.