Heparin

also known as unfractionated heparin · UFH · Heparin Sodium · Low molecular weight heparin · sodium heparin · Heparin sodium APP · clexan · Enoxalow · +38 more

Other / unclassified

Developed for: COVID-19 · venous thromboembolism · infectious disease with sepsis · pulmonary embolism · pneumonia · hemorrhagic disease · interstitial cystitis · myocardial infarction
+67 more
· blood coagulation disease · coronary artery disorder · ST-elevation myocardial infarction · acute lung injury · acute respiratory distress syndrome · brain aneurysm · intermediate coronary syndrome · thrombotic disease · arterial occlusion · arteriovenous hemangioma/malformation · cardiac valvular defect · ischemic stroke · morbid obesity · prosthesis-related infectious disease · respiratory failure · severe acute respiratory syndrome · thrombophilia · urinary tract infection · viral pneumonia · abdominal aortic aneurysm · acquired aneurysmal subarachnoid hemorrhage · acute chest syndrome · acute intestinal ischemia · acute kidney injury · acute pancreatitis · anaphylaxis · angioedema · arterial disorder · atrial fibrillation · basilar artery occlusion · cardiogenic shock · cardiovascular disorder · cirrhosis of liver · colorectal cancer · congenital total pulmonary venous return anomaly · developmental delay, behavioral abnormalities, and neuropsychiatric disorders · disseminated intravascular coagulation · end stage renal failure · gram-negative bacterial infections · infertility disorder · ischemic disease · isolated mesenteric vein thrombosis · lung disorder · pelvis syndrome · peripheral vascular disease · pregnancy disorder · pregnancy disorder with abortive outcome · pregnancy loss, recurrent, 4 · stroke disorder · vulvodynia · acute coronary syndrome · acute myocardial infarction · adhesions of uterus · carotid artery dissection · cerebral sinovenous thrombosis · chronic renal failure syndrome · coronary artery intramyocardial course · dialysis disequilibrium syndrome · habitual spontaneous abortion · heart disorder · impaired renal function disease · intracranial embolism · portal vein thrombosis · pseudotumor cerebri · type 1 diabetes mellitus · vascular occlusion disorder · vertebral artery dissection
Investigated by: Azidus Brasil · University of Manitoba · Australian National University · Blau Farmaceutica S.A. · Canadian Institutes of Health Research (CIHR) · Frederick Health
+305 more
· University of Sao Paulo · University of Sao Paulo General Hospital · Academic Medical Center - University of Amsterdam · Assistance Publique - Hôpitaux de Paris · Canadian Critical Care Trials Group · Clinica San Camilo, Argentina · CorMedix · Ezhou Central Hospital · German Heart Center Munich · GlaxoSmithKline · Guangdong Provincial People's Hospital · Hamilton Health Sciences Corporation · Hanyang University · Hubei University of Medicine · Jiangling People's Hospital · Jiangxia First People's Hospital · Jingzhou Central Hospital · Laohekou First Hospital · National Cancer Institute (NCI) · People's Hospital of Jingshan · Renmin Hospital of Wuhan University · Scripps Health · Shanghai First Maternity and Infant Hospital · Shiyan People's Hospital · Songzi People's Hospital · Southlake Health · St Vincent's Hospital Melbourne · Swedish Orphan Biovitrum · The Central Hospital of Enshi Tujia And Miao Autonomous Prefecture · The Central Hospital of Huanggang · Unity Health Toronto · University College Hospital Galway · University Health Network, Toronto · University Medicine Greifswald · University of Alberta · University of Vermont Medical Center · Urigen · West China Hospital · Wuhan Central Hospital · Wuhan Hospital of Traditional Chinese Medicine · Wuhan No.1 Hospital · Wuhan No.6 Hospital · Wuhan Puren Hospital · Wuxue First People's Hospital · Xiangyang Central Hospital · Xianning Central Hospital · Xianning First People's Hospital · Xiantao First People's Hospital · Xiaotong Hou · Yichang Central People's Hospital · Adiyaman University Research Hospital · Ain Shams University · Al Ain Hospital · Alberta Health services · Allied Hospital Faisalabad · American College of Emergency Physicians · Amsterdam UMC, location VUmc · Anlu People's Hospital · Anlu Puai Hospital · Assiut University · Astes · Aurora Clinical Research · Australian and New Zealand Intensive Care Research Centre · Avanti PC · Azienda Ospedaliera di Lecco · Barnes-Jewish Hospital · Basma Rabiey · Baylor Research Institute · Beaumont Hospital · Beijing Anzhen Hospital · Beijing Friendship Hospital · Beijing Tiantan Hospital · Beijing Tsinghua Changgeng Hospital · Ben-Gurion University of the Negev · all 311 on the full record

Regulatory milestones approvals, filings & regulatory actions · 9 recorded

Milestone	Jurisdiction	Brand	Indication	Date	Sentence it was read from
Label expansion	US (FDA)	HEPARIN SODIUM 25,000 UNITS IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER	—	1989-06-23	fda.gov ↗
Label expansions (3)	US (FDA)	HEPARIN SODIUM	—	1983-12-19 – 1986-04-11	fda.gov ↗
Label expansion	US (FDA)	HEPARIN SODIUM 25,000 UNITS IN SODIUM CHLORIDE 0.45%	—	1985-07-29	fda.gov ↗
Label expansion	US (FDA)	HEPARIN SODIUM 25,000 UNITS AND DEXTROSE 5% IN PLASTIC CONTAINER	—	1985-07-09	fda.gov ↗
Label expansions (2)	US (FDA)	HEPARIN LOCK FLUSH	—	1981-05-15 – 1985-05-21	fda.gov ↗
Approved	US (FDA)	HEPARIN SODIUM	—	1939-02-09	fda.gov ↗

Trials 165 · started per year

today

US approved 1939

1937193819391940194119421943194419451946194719481949195019511952195319541955195619571958195919601961196219631964196519661967196819691970197119721973197419751976197719781979198019811982198319841985198619871988198919901991199219931994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027202820292030

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 05 trials
Phase 0	NCT06112262	Dec 2023 → Sep 2025 overdue	—	Basma Rabiey	Not yet recruiting	No outcome recorded
Phase 0	NCT05178550	Dec 2021 → Jan 2022	—	Novo Nordisk A/S	Completed	No outcome recorded
Phase 0	NCT04490239	Oct → Nov 2020	COVID-19	Joshua Sharp	Completed	No outcome recorded
Phase 0	NCT02246270	Nov 2017 → Dec 2025	urinary tract infection	University of Oklahoma	Completed	No outcome recorded
Phase 0	NCT02970032	Nov 2016 → Sep 2017	pulmonary embolism, venous thromboembolism	University of Utah	Completed	No outcome recorded
Phase 114 trials
Phase 1	NCT06517563	Aug → Dec 2024	blood coagulation disease	VarmX B.V.	Completed	No outcome recorded
Phase 1	NCT05788913	Jun 2023	—	Blau Farmaceutica S.A.	Unknown	No outcome recorded
Phase 1	NCT05788900	Jun 2023	—	Blau Farmaceutica S.A.	Unknown	No outcome recorded
Phase 1	NCT03125187	Feb 2021	—	Uniao Quimica	Suspended	No outcome recorded
Phase 1	NCT02435732	Dec 2020 → May 2021	kidney failure	University of Wisconsin, Madison	Unknown	No outcome recorded
Phase 1	NCT02271126	Sep 2014 → Sep 2016	—	Policlinico Hospital	Completed	No outcome recorded
Phase 1	NCT01692158	Mar → Nov 2013	—	Azidus Brasil	Completed	No outcome recorded
Phase 1	NCT01692171	Feb → Oct 2013	—	Azidus Brasil	Completed	No outcome recorded
Phase 1	NCT01651923	Feb → Apr 2013	—	Azidus Brasil	Unknown	No outcome recorded
Phase 1	NCT01652638	Feb → Apr 2013	—	Azidus Brasil	Unknown	No outcome recorded
Phase 1	NCT01598883	Jun 2012 → Dec 2014	—	Massachusetts General Hospital	Completed	No outcome recorded
Phase 1	NCT01513200	Jan → Feb 2012	—	Stealth BioTherapeutics Inc.	Completed	No outcome recorded
Phase 1	NCT01163097	Jul 2010 → Jan 2011	mucositis	Swedish Orphan Biovitrum	Completed	No outcome recorded
Phase 1	NCT00361348	Dec 2005 → Jul 2006	—	Swedish Orphan Biovitrum	Completed	No outcome recorded

Phase 1/23 trials
Phase 1/2	NCT04511923	Dec 2020 → Dec 2021	COVID-19, acute lung injury, acute respiratory distress syndrome	University College Hospital Galway	Completed	No outcome recorded
Phase 1/2	NCT04397289	Feb 2018 → Mar 2021	cirrhosis of liver, hemorrhagic disease, portal hypertension, thrombotic disease	First Affiliated Hospital Xi'an Jiaotong University	Completed	No outcome recorded
Phase 1/2	NCT02940444	Jun 2016 → Jun 2018	venous thromboembolism	West China Hospital	Unknown	No outcome recorded
Phase 219 trials
Phase 2	NCT06381661	May 2026 → Jun 2028 expected	infectious disease with sepsis	Assistance Publique - Hôpitaux de Paris	Not yet recruiting	No outcome recorded
Phase 2	NCT06080074	Apr 2025 → Sep 2027 expected	cardiogenic shock, cardiomyopathy, congenital heart disease, heart failure	Stanford University	Recruiting	No outcome recorded
Phase 2	NCT05737121	May 2023 → Jun 2026 overdue	interstitial cystitis	Vaneltix Pharma, Inc.	Recruiting	No outcome recorded
Phase 2	NCT07074821	Mar 2023 → Feb 2024	—	Oman Ministry of Health	Completed	No outcome recorded
Phase 2	NCT04842292	May → Sep 2021	COVID-19	Brittany Bissell	Terminated	No outcome recorded
Phase 2	NCT04313790	Aug 2020 → Oct 2022	infectious disease with sepsis	Damanhour University	Completed	No outcome recorded
Phase 2	NCT04466670	Jul 2020 → Dec 2021	COVID-19	University of Sao Paulo General Hospital	Unknown	No outcome recorded
Phase 2	NCT04344756	Apr → Jul 2020	pneumonia	Assistance Publique - Hôpitaux de Paris	Unknown	No outcome recorded
Phase 2	NCT03633994	Aug 2018 → Dec 2019	urinary tract infection	The Christ Hospital	Unknown	No outcome recorded
Phase 2	NCT03378466	Mar 2018 → Dec 2021	infectious disease with sepsis	University of Manitoba	Terminated	No outcome recorded
Phase 2	NCT02501434	Apr 2016 → Jan 2023	acquired aneurysmal subarachnoid hemorrhage, brain aneurysm, developmental delay, behavioral abnormalities, and neuropsychiatric disorders, heparin-induced thrombocytopenia +1	Robert F. James	Suspended	No outcome recorded
Phase 2	NCT02591199	Sep 2015 → May 2018	interstitial cystitis	Urigen	Terminated	No outcome recorded
Phase 2	NCT02098993	May 2014 → Jun 2018	acute chest syndrome, sickle cell disease	Craig Seaman	Terminated	No outcome recorded
Phase 2	NCT01048177	Dec 2012 → Jun 2014	vulvodynia	Scripps Health	Withdrawn	No outcome recorded
Phase 2	NCT01648036	Jul 2012 → Jan 2014	infectious disease with sepsis	University of Manitoba	Completed	No outcome recorded
Phase 2	NCT00317070	Apr 2006 → Feb 2009	interstitial cystitis	Nova Scotia Health Authority	Terminated	No outcome recorded
Phase 2	NCT00256542	Jan → Sep 2006	interstitial cystitis, pelvis syndrome	Urigen	Completed	No outcome recorded
Phase 2	NCT00133731	Sep 2004 → Oct 2005	—	Sanofi	Completed	No outcome recorded
Phase 2	NCT00060554	Apr 2003 → ?	coronary artery disorder, myocardial infarction	Schering-Plough	Withdrawn	No outcome recorded

Phase 2/311 trials
Phase 2/3	NCT05184101	Aug → Dec 2023	COVID-19	Australian National University	Withdrawn	No outcome recorded
Phase 2/3	NCT05204550	Jan 2023 → Dec 2024	COVID-19	Murdoch Childrens Research Institute	Completed	No outcome recorded
Phase 2/3	NCT04273607	Sep 2022 → Dec 2026 expected	—	Damian Ratano	Recruiting	No outcome recorded
Phase 2/3	NCT05255848	Jun → Aug 2022	pneumonia	Lady Reading Hospital, Pakistan	Unknown	No outcome recorded
Phase 2/3	NCT04545541	Nov 2020 → Apr 2024	COVID-19, respiratory failure	Australian National University	Completed	No outcome recorded
Phase 2/3	NCT04635241	Jun 2020 → Nov 2023	COVID-19	Australian National University	Completed	No outcome recorded
Phase 2/3	NCT04372589	May 2020 → May 2021	COVID-19, pneumonia	University of Manitoba	Completed	No outcome recorded
Phase 2/3	NCT02040818	Nov 2013 → Jan 2017	—	University of California, San Diego	Withdrawn	No outcome recorded
Phase 2/3	NCT01034488	Aug 2010 → Dec 2011	—	Azidus Brasil	Unknown	No outcome recorded
Phase 2/3	NCT00928213	Aug 2009 → Dec 2010	preeclampsia	Ben-Gurion University of the Negev	Unknown	No outcome recorded
Phase 2/3	NCT00701623	Jun 2008	—	Azidus Brasil	Withdrawn	No outcome recorded

Phase 332 trials
Phase 3	NCT07162064	Aug 2025 → Jan 2026	ischemic stroke	Xiang Luo	Completed	No outcome recorded
Phase 3	NCT05848713	Oct 2023 → Mar 2028 expected	pneumonia	University of Manitoba	Recruiting	No outcome recorded
Phase 3	NCT05886998	Jun 2023 → Jun 2024	acute lung injury	Ain Shams University	Completed	No outcome recorded
Phase 3	NCT04861922	May 2021 → Dec 2023	gram-negative bacterial infections, infectious disease with sepsis	The Third Xiangya Hospital of Central South University	Unknown	No outcome recorded
Phase 3	NCT04528888	Nov 2020 → Jun 2021	COVID-19, blood coagulation disease, viral pneumonia	Massimo Girardis	Unknown	No outcome recorded
Phase 3	NCT04600141	Nov 2020 → Oct 2021	COVID-19	University of Sao Paulo	Completed	No outcome recorded
Phase 3	NCT04485429	Jul 2020 → Dec 2022	COVID-19	D'Or Institute for Research and Education	Withdrawn	No outcome recorded
Phase 3	NCT04444700	Jul 2020 → May 2021	COVID-19, blood coagulation disease, severe acute respiratory syndrome, venous thromboembolism	University of Sao Paulo General Hospital	Completed	No outcome recorded
Phase 3	NCT04362085	May 2020 → May 2021	COVID-19	Unity Health Toronto	Completed	No outcome recorded
Phase 3	NCT02654561	Apr 2018 → Dec 2024	disseminated intravascular coagulation, infectious disease with sepsis	China Medical University, China	Unknown	No outcome recorded
Phase 3	NCT02798471	Mar 2017 → May 2022	pulmonary embolism, venous thromboembolism	Daiichi Sankyo	Completed	No outcome recorded
Phase 3	NCT02735707	Apr 2016 → Feb 2026 overdue	pneumonia	UMC Utrecht	Recruiting	No outcome recorded
Phase 3	NCT03465085	Feb 2016 → Jan 2018	acute respiratory distress syndrome, severe acute respiratory syndrome	Beni-Suef University	Completed	No outcome recorded
Phase 3	NCT02036255	May 2015 → Jul 2017	infectious disease	University Hospital Brussels	Completed	No outcome recorded
Phase 3	NCT01773083	Oct 2013 → Oct 2016	lung disorder	Academic Medical Center - University of Amsterdam	Terminated	No outcome recorded
Phase 3	NCT01976988	Sep 2013 → May 2015	venous thromboembolism	Cedars-Sinai Medical Center	Completed	No outcome recorded
Phase 3	NCT02135770	Jan 2013 → Jun 2014	infectious disease with sepsis	Indonesia University	Completed	No outcome recorded
Phase 3	NCT01454869	Feb → Jun 2012	—	Tehran University of Medical Sciences	Withdrawn	No outcome recorded
Phase 3	NCT00912483	May → Nov 2010	venous thromboembolism	Azidus Brasil	Withdrawn	No outcome recorded
Phase 3	NCT01356329	Oct 2009 → Aug 2016	female reproductive system neoplasm	National Guard Health Affairs	Suspended	No outcome recorded
Phase 3	NCT00894959	Jul → Sep 2009	cardiac valvular defect	Azidus Brasil	Completed	No outcome recorded
Phase 3	NCT00894985	Jun → Sep 2009	cardiac valvular defect	Azidus Brasil	Completed	No outcome recorded
Phase 3	NCT00905216	Jun → Sep 2009	—	Azidus Brasil	Unknown	No outcome recorded
Phase 3	NCT01260519	Jul 2008 → Oct 2010	—	Prince Sultan Cardiac Center, Adult Cardiology Department.	Completed	No outcome recorded
Phase 3	NCT00911157	Jun 2008 → Nov 2009	venous thromboembolism	GlaxoSmithKline	Completed	No outcome recorded
Phase 3	NCT00981409	Jul 2007 → Dec 2008	pulmonary embolism	GlaxoSmithKline	Completed	No outcome recorded
Phase 3	NCT00182364	Feb 2003 → Feb 2004	venous thromboembolism	Hamilton Health Sciences Corporation	Completed	No outcome recorded
Phase 3	NCT00587444	Jun 2001 → Oct 2007	—	Mayo Clinic	Completed	No outcome recorded
Phase 3	NCT02181985	May 2000 → Apr 2001	myocardial infarction	Boehringer Ingelheim	Completed	No outcome recorded
Phase 3	NCT00182403	Sep 1998 → May 2004	pulmonary embolism, venous thromboembolism	McMaster University	Completed	No outcome recorded
Phase 3	NCT00271401	Jul 1996 → Sep 1997	—	Centocor, Inc.	Completed	No outcome recorded
Phase 3	NCT00427310	Mar 1984 → Sep 1989	colorectal cancer	NSABP Foundation Inc	Completed	No outcome recorded

Phase 446 trials
Phase 4	NCT07609771	Jun → Nov 2026 expected	acute pancreatitis	Allied Hospital Faisalabad	Not yet recruiting	No outcome recorded
Phase 4	NCT06714864	Jul 2025 → Jul 2028 expected	prosthesis-related infectious disease	CorMedix	Recruiting	No outcome recorded
Phase 4	NCT06174961	Sep 2023 → Feb 2024	blood coagulation disease	Kristian Karstoft	Completed	No outcome recorded
Phase 4	NCT05604859	Aug 2022 → Dec 2023	—	Qin Ning	Unknown	No outcome recorded
Phase 4	NCT05247424	Mar 2022 → Feb 2025	ST-elevation myocardial infarction	University Medical Centre Ljubljana	Completed	No outcome recorded
Phase 4	NCT04723563	Feb → Aug 2021	COVID-19, viral pneumonia	Frederick Health	Completed	No outcome recorded
Phase 4	NCT04406389	Oct 2020 → Apr 2021	COVID-19	Weill Medical College of Cornell University	Terminated	No outcome recorded
Phase 4	NCT04505774	Sep 2020 → Aug 2023	COVID-19	Matthew Neal MD	Completed	No outcome recorded
Phase 4	NCT04409834	Aug 2020 → Mar 2022	COVID-19, thrombotic disease, venous thromboembolism	The TIMI Study Group	Completed	No outcome recorded
Phase 4	NCT04394377	Jun 2020 → Mar 2021	COVID-19	Brazilian Clinical Research Institute	Completed	No outcome recorded
Phase 4	NCT04530578	Jun → Oct 2020	COVID-19, pneumonia	Clinica San Camilo, Argentina	Unknown	No outcome recorded
Phase 4	NCT04397510	Jun 2020 → Dec 2021	COVID-19, acute lung injury, acute respiratory distress syndrome	Frederick Health	Terminated	No outcome recorded
Phase 4	NCT04367831	May 2020 → May 2021	COVID-19, thrombotic disease, venous thromboembolism	Columbia University	Completed	No outcome recorded
Phase 4	NCT04061798	Mar 2020 → Apr 2024	abdominal aortic aneurysm	Dijklander Ziekenhuis	Terminated	No outcome recorded
Phase 4	NCT03752437	Oct 2019 → Sep 2021	—	Astes	Completed	No outcome recorded
Phase 4	NCT03664180	Jan 2019 → Nov 2022	ST-elevation myocardial infarction	Beijing Anzhen Hospital	Completed	No outcome recorded
Phase 4	NCT04496362	Oct 2018 → Feb 2025 overdue	respiratory failure	Baylor Research Institute	Active not recruiting	No outcome recorded
Phase 4	NCT03426982	Mar → Oct 2018	bleeding disorder, vascular-type, myocardial infarction, stroke disorder, venous thromboembolism	Wuhan Asia Heart Hospital	Unknown	No outcome recorded
Phase 4	NCT03006562	Jul 2017 → Nov 2019	lymphocele, prostate cancer, pulmonary embolism, venous thromboembolism	Johns Hopkins University	Terminated	No outcome recorded
Phase 4	NCT03113708	Apr → May 2017	hemorrhagic disease, hyperheparinemia	Adiyaman University Research Hospital	Unknown	No outcome recorded
Phase 4	NCT02812355	Jan 2017 → Jan 2019	ischemic disease	Azienda Ospedaliera di Lecco	Unknown	No outcome recorded
Phase 4	NCT02986594	Nov 2016 → Oct 2019	thrombophilia	Shanghai First Maternity and Infant Hospital	Unknown	No outcome recorded
Phase 4	NCT03120715	Jul 2016 → Jun 2017	infertility disorder	Nanfang Hospital, Southern Medical University	Unknown	No outcome recorded
Phase 4	NCT02675647	Dec 2015 → Dec 2016	morbid obesity	University Hospital, Strasbourg, France	Completed	No outcome recorded
Phase 4	NCT02645240	Oct 2015 → Jul 2017	acute intestinal ischemia	Mansoura University	Completed	No outcome recorded
Phase 4	NCT02570243	Feb 2015 → Sep 2017	—	University of Patras	Completed	No outcome recorded
Phase 4	NCT02990403	Oct 2014 → Jun 2017	pregnancy loss, recurrent, 4	Shanghai First Maternity and Infant Hospital	Unknown	No outcome recorded
Phase 4	NCT01862978	May 2013 → May 2015	ischemic stroke	University Hospital, Martin	Unknown	No outcome recorded
Phase 4	NCT01823393	Jan 2013 → Oct 2016	aortic valve stenosis	University Hospital, Montpellier	Terminated	No outcome recorded
Phase 4	NCT01794767	Jan 2013 → Aug 2014	phlebitis	University of Florence	Suspended	No outcome recorded
Phase 4	NCT01729559	Nov 2012 → Sep 2014	pulmonary embolism, venous thromboembolism	Scripps Health	Completed	No outcome recorded
Phase 4	NCT05223244	Oct 2011 → Apr 2019	interstitial cystitis	Endeavor Health	Completed	No outcome recorded
Phase 4	NCT02493504	Jan 2011 → Apr 2012	arteriovenous hemangioma/malformation	Fatemeh Hoseinzadegan	Completed	No outcome recorded
Phase 4	NCT01980316	Apr 2010 → Aug 2011	cardiovascular disorder	Xinfeng Liu	Completed	No outcome recorded
Phase 4	NCT01694459	Jan 2010 → Dec 2012	intermediate coronary syndrome, myocardial infarction	San Filippo Neri General Hospital	Unknown	No outcome recorded
Phase 4	NCT01214772	May → Sep 2009	pregnancy disorder, thrombophilia	Yazd Medical University	Completed	No outcome recorded
Phase 4	NCT00735280	Aug 2008 → Mar 2010	coronary artery disorder	German Heart Center Munich	Completed	No outcome recorded
Phase 4	NCT01634438	Jul 2008 → Dec 2010	—	University of Alberta	Completed	No outcome recorded
Phase 4	NCT00657475	Jun 2008 → Feb 2013	—	University Hospital, Bordeaux	Completed	No outcome recorded
Phase 4	NCT00373451	Jul 2006 → May 2011	coronary artery disorder, myocardial infarction	German Heart Center Munich	Completed	No outcome recorded
Phase 4	NCT00253396	Oct 2005 → Jan 2007	—	Hamilton Health Sciences Corporation	Completed	No outcome recorded
Phase 4	NCT00188773	Jan 2004 → Aug 2007	metabolic syndrome X	University Health Network, Toronto	Completed	No outcome recorded
Phase 4	NCT00196469	Dec 2003 → Mar 2007	hemorrhagic disease	University Medicine Greifswald	Unknown	No outcome recorded
Phase 4	NCT00439855	Sep 2003 → Feb 2006	coronary artery disorder	Triemli Hospital	Completed	No outcome recorded
Phase 4	NCT00253851	Jul 2003 → May 2011	osteoarthritis, venous thromboembolism	Ottawa Hospital Research Institute	Completed	No outcome recorded
Phase 4	NCT00196417	Jan 2003 → Nov 2005	heparin-induced thrombocytopenia	University Medicine Greifswald	Unknown	No outcome recorded

Phase not applicable34 trials
—	NCT07361783	Jan 2026 → Dec 2029 expected	ST-elevation myocardial infarction	Chen Jing	Recruiting	No outcome recorded
—	NCT06753786	Oct 2024 → Dec 2028 expected	intracerebral hemorrhage, pulmonary embolism, venous thromboembolism	Pirogov Russian National Research Medical University	Recruiting	No outcome recorded
—	NCT06549842	Aug 2024 → Feb 2026	arterial occlusion, hemorrhagic disease	Regional Hospital of Scranton	Completed	No outcome recorded
—	NCT06276010	Jul 2024 → Nov 2026 expected	—	Xiaotong Hou	Recruiting	No outcome recorded
—	NCT06275555	Jun 2024 → Dec 2026 expected	—	Xiaotong Hou	Recruiting	No outcome recorded
—	NCT05634057	Jan 2024 → Dec 2025 overdue	infectious disease with sepsis	Chen Ying	Recruiting	No outcome recorded
—	NCT06484634	Dec 2023 → May 2024	pregnancy disorder with abortive outcome	RESnTEC, Institute of Research	Completed	No outcome recorded
—	NCT05749393	Apr 2023 → Mar 2024	brain aneurysm	The First Affiliated Hospital with Nanjing Medical University	Unknown	No outcome recorded
—	NCT05329155	Jul 2022 → Aug 2023	ST-elevation myocardial infarction	Renmin Hospital of Wuhan University	Completed	No outcome recorded
—	NCT05209841	Apr 2022 → Jul 2026 overdue	—	Consorci Sanitari de l'Alt Penedès i Garraf	Recruiting	No outcome recorded
—	NCT04764396	Mar → Apr 2021	pancreatic neoplasm	University of Michigan	Terminated	No outcome recorded
—	NCT04767113	Mar 2021 → Aug 2022	venous thromboembolism	Guangdong Provincial People's Hospital	Completed	No outcome recorded
—	NCT04139525	Sep 2020 → Dec 2022	end stage renal failure	Marija Malgaj Vrečko	Unknown	No outcome recorded
—	NCT04561648	Aug 2020 → Dec 2025	arterial occlusion	Instituto Nacional de Cardiologia Ignacio Chavez	Unknown	No outcome recorded
—	NCT04487990	Jun 2020 → Mar 2021	COVID-19, acute kidney injury	University of Sao Paulo General Hospital	Completed	No outcome recorded
—	NCT04241380	Feb 2020 → Oct 2021	congenital total pulmonary venous return anomaly	Guangdong Provincial People's Hospital	Unknown	No outcome recorded
—	NCT04227678	Dec 2019 → Dec 2026 expected	familial lipoprotein lipase deficiency	University of Sherbrooke	Recruiting	No outcome recorded
—	NCT04121611	Oct 2019 → Oct 2021	basilar artery occlusion	Sunnybrook Health Sciences Centre	Unknown	No outcome recorded
—	NCT03483207	Apr 2018 → Dec 2019	isolated mesenteric vein thrombosis	Assiut University	Unknown	No outcome recorded
—	NCT04355273	Jan → Feb 2018	hyperheparinemia	Yangzhou University	Completed	No outcome recorded
—	NCT02966080	Dec 2016 → Dec 2020	acute respiratory failure, hemorrhagic disease	University of Arizona	Withdrawn	No outcome recorded
—	NCT03306836	Sep 2016 → Sep 2020	arteriovenous hemangioma/malformation, brain aneurysm	Beijing Tiantan Hospital	Unknown	No outcome recorded
—	NCT02477072	Sep 2015 → Jan 2016	peripheral vascular disease	University of Montreal Hospital Centre (CHUM)	Completed	No outcome recorded
—	NCT03302195	Aug 2015 → Dec 2024 overdue	obesity disorder	Laval University	Recruiting	No outcome recorded
—	NCT02497326	Apr → Dec 2015	—	King Edward Medical University	Unknown	No outcome recorded
—	NCT01839578	May 2013 → Nov 2014	infectious disease with sepsis	Hospices Civils de Lyon	Unknown	No outcome recorded
—	NCT03350737	Feb 2013 → Dec 2019	intermediate coronary syndrome	Clinical Centre of Serbia	Completed	No outcome recorded
—	NCT01394458	Aug 2011 → Nov 2013	bacterial infectious disease, prosthesis-related infectious disease	University of Manitoba	Completed	No outcome recorded
—	NCT01363193	Jul 2011 → Dec 2014	atrial fibrillation, intermediate coronary syndrome, morbid obesity, venous thromboembolism	Nazareth Hospital	Unknown	No outcome recorded
—	NCT00657228	Dec 2009 → Dec 2010	anaphylaxis	University of Missouri, Kansas City	Withdrawn	No outcome recorded
—	NCT00848796	Sep 2006 → Dec 2007	—	Southlake Health	Completed	No outcome recorded
—	NCT00494156	Jul 2003 → Jul 2008	arterial disorder	C. Clay Cothren, MD	Withdrawn	No outcome recorded
—	NCT00004694	Jan 1994 → Sep 1998	angioedema	University of Iowa	Completed	No outcome recorded
—	NCT00378781	—	cancer	M.D. Anderson Cancer Center	Withdrawn	No outcome recorded

Phase not stated1 trial
—	NCT06707480	—	—	CorMedix	No longer available	No outcome recorded

Also used as a comparator or background therapy in 224 trials

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 03 trials
Phase 0	NCT05029596 Comparator	Feb 2020 → Mar 2023	cancer	University of Texas Southwestern Medical Center	Completed	No outcome recorded
Phase 0	NCT03516656 Comparator	Mar 2018 → Jun 2019	pulmonary embolism, venous thromboembolism	University of Utah	Completed	No outcome recorded
Phase 0	NCT03963336 Comparator	Jul 2017 → Jul 2018	pseudotumor cerebri	Fayoum University	Completed	No outcome recorded
Phase 15 trials
Phase 1	NCT03707418 Comparator	Apr → Jun 2021	—	Johns Hopkins University	Withdrawn	No outcome recorded
Phase 1	NCT04419493 Background	Jun 2020 → Jun 2021	—	Boehringer Ingelheim	Completed	No outcome recorded
Phase 1	NCT02687256 Background	Mar 2016 → Nov 2017	type 1 diabetes mellitus	Stanford University	Completed	No outcome recorded
Phase 1	NCT00614679 Background	Oct 2006 → Dec 2008	end stage renal failure	University of California, San Diego	Completed	No outcome recorded
Phase 1	NCT00001713 Background	Feb 1998 → Jan 2006	thrombophlebitis	National Institutes of Health Clinical Center (CC)	Completed	No outcome recorded
Phase 1/28 trials
Phase 1/2	NCT04743011 Comparator	Jun → Nov 2021	COVID-19	UPECLIN HC FM Botucatu Unesp	Completed	No outcome recorded
Phase 1/2	NCT04355728 Background	Apr → Oct 2020	COVID-19, acute respiratory distress syndrome	Camillo Ricordi	Completed	No outcome recorded
Phase 1/2	NCT04042324 Background	Sep 2019 → Jan 2020	end stage renal failure	Rockwell Medical Technologies, Inc.	Completed	No outcome recorded
Phase 1/2	NCT03000673 Comparator	May → Oct 2017	—	Bristol-Myers Squibb	Completed	No outcome recorded
Phase 1/2	NCT02365285 Background	Mar 2015 → Oct 2017	obesity disorder	Vanderbilt University Medical Center	Completed	No outcome recorded
Phase 1/2	NCT02227329 Comparator	Jul 2014 → Oct 2016	—	Mayo Clinic	Terminated	No outcome recorded
Phase 1/2	NCT02206087 Background	Jun 2014 → Mar 2016	—	AMAG Pharmaceuticals, Inc.	Completed	No outcome recorded
Phase 1/2	NCT00790842 Background	Jan 2009 → Sep 2017	plasma cell myeloma	PrECOG, LLC.	Terminated	No outcome recorded

Phase 227 trials
Phase 2	NCT05959252 Comparator	May 2024 → Jun 2026 overdue	—	Sydney Local Health District	Recruiting	No outcome recorded
Phase 2	NCT05555641 Comparator	Dec 2022 → Oct 2024	—	Xiaobo Yang, MD	Unknown	No outcome recorded
Phase 2	NCT05602129 Comparator	Nov 2022 → Oct 2023	—	Haisco Pharmaceutical Group Co., Ltd.	Unknown	No outcome recorded
Phase 2	NCT03867851 Comparator	Feb 2021 → May 2024	type 1 diabetes mellitus	TikoMed AB	Terminated	No outcome recorded
Phase 2	NCT05414305 Background	Oct 2020 → Dec 2023	interstitial cystitis	Walter Reed National Military Medical Center	Completed	No outcome recorded
Phase 2	NCT04401176 Comparator	Sep 2020 → Jun 2023	interstitial cystitis	Walter Reed National Military Medical Center	Completed	No outcome recorded
Phase 2	NCT03854266 Comparator	Mar 2020 → Mar 2023	pulmonary embolism	University of Aarhus	Unknown	No outcome recorded
Phase 2	NCT03672006 Comparator	Apr → Dec 2019	venous thromboembolism	Medical College of Wisconsin	Completed	No outcome recorded
Phase 2	NCT03178864 Comparator	Mar 2019 → Oct 2022	cerebral sinovenous thrombosis	University of British Columbia	Completed	No outcome recorded
Phase 2	NCT03772613 Comparator	Feb 2019 → Oct 2021	coronary artery disorder, hemorrhagic disease, ischemic disease	Mayo Clinic	Completed	No outcome recorded
Phase 2	NCT03114722 Comparator	Jul 2017 → Jul 2018	vascular occlusion disorder	National University Hospital, Singapore	Unknown	No outcome recorded
Phase 2	NCT02870738 Comparator	Apr 2017 → Feb 2026 overdue	interstitial cystitis	Corewell Health East	Active not recruiting	No outcome recorded
Phase 2	NCT02159287 Comparator	Jan 2014 → Feb 2016	intracranial embolism	Shiraz University of Medical Sciences	Unknown	No outcome recorded
Phase 2	NCT01662908 Comparator	Aug 2012 → Jan 2014	venous thromboembolism	Daiichi Sankyo	Completed	No outcome recorded
Phase 2	NCT01382888 Comparator	Jul 2011 → Apr 2014	—	Cyathus Exquirere Pharmaforschungsgmbh	Terminated	No outcome recorded
Phase 2	NCT01234285 Comparator	Dec 2010 → Apr 2013	infectious disease with sepsis	University of Colorado, Denver	Withdrawn	No outcome recorded
Phase 2	NCT00911300 Comparator	Aug 2009 → Sep 2011	atrial fibrillation	GlaxoSmithKline	Completed	No outcome recorded
Phase 2	NCT00932100 Comparator	Jul 2009 → Jan 2011	acute coronary syndrome	Regado Biosciences, Inc.	Completed	No outcome recorded
Phase 2	NCT00818753 Comparator	Jan 2009 → Aug 2010	—	Boehringer Ingelheim	Completed	No outcome recorded
Phase 2	NCT00789308 Comparator	Jul 2008 → Jul 2013	type 1 diabetes mellitus	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
Phase 2	NCT00790439 Comparator	Jul 2008 → Oct 2009	type 1 diabetes mellitus	National Institute of Allergy and Infectious Diseases (NIAID)	Withdrawn	No outcome recorded
Phase 2	NCT00715455 Comparator	Oct 2007 → Oct 2008	coronary artery disorder	Regado Biosciences, Inc.	Completed	No outcome recorded
Phase 2	NCT00543400 Comparator	Sep 2007 → Apr 2009	coronary artery disorder	Momenta Pharmaceuticals, Inc.	Completed	No outcome recorded
Phase 2	NCT00317395 Comparator	Jun 2006 → Oct 2008	coronary artery disorder	Sanofi	Completed	No outcome recorded
Phase 2	NCT01051778 Comparator	Jun 2006 → Nov 2009	habitual spontaneous abortion	Cairo University	Completed	No outcome recorded
Phase 2	NCT00445211 Comparator	Jan 2006 → Mar 2008	cardiogenic shock	Corewell Health East	Terminated	No outcome recorded
Phase 2	NCT00508924 Comparator	Aug 2005 → Oct 2006	intermediate coronary syndrome	Tanabe Pharma Corporation	Completed	No outcome recorded

Phase 2/39 trials
Phase 2/3	NCT06662253 Comparator	Jan 2025 → Jun 2026 overdue	venous thromboembolism	Alexandre Tran	Not yet recruiting	No outcome recorded
Phase 2/3	NCT05188339 Comparator	Jul → Dec 2022	venous thromboembolism	Chang Gung Memorial Hospital	Unknown	No outcome recorded
Phase 2/3	NCT05226442 Comparator	Dec 2021 → Jul 2024	blood coagulation disease	Medical University of Vienna	Completed	No outcome recorded
Phase 2/3	NCT04655586 Comparator	Dec 2020 → Dec 2021	COVID-19	ARCA Biopharma, Inc.	Completed	No outcome recorded
Phase 2/3	NCT02529774 Background	Sep 2015 → Sep 2020	metastasis from malignant tumor of colon	Ye Xu	Unknown	No outcome recorded
Phase 2/3	NCT01204333 Comparator	Sep 2011 → Dec 2016	intracranial sinus thrombosis	Jan Stam, MD, PhD	Terminated	No outcome recorded
Phase 2/3	NCT00934167 Comparator	May → Nov 2010	venous thromboembolism	Azidus Brasil	Unknown	No outcome recorded
Phase 2/3	NCT00828776 Comparator	Sep 2007 → Feb 2008	chronic renal failure syndrome	Azidus Brasil	Completed	No outcome recorded
Phase 2/3	NCT00329433 Comparator	May 2006 → Oct 2008	venous thromboembolism	Washington University School of Medicine	Completed	No outcome recorded

Phase 356 trials
Phase 3	NCT06453876 Comparator	Jun 2026 → Jun 2028 expected	pulmonary embolism	Jesper Kjaergaard	Recruiting	No outcome recorded
Phase 3	NCT06822426 Comparator	May 2025 → Jan 2028 expected	—	CorMedix	Recruiting	No outcome recorded
Phase 3	NCT05658874 Background	Dec 2022 → Dec 2024	interstitial cystitis, levator syndrome	Jocelyn Fitzgerald	Terminated	No outcome recorded
Phase 3	NCT05591872 Comparator	May 2022 → Apr 2023	arterial occlusion	Tabba Heart Institute	Unknown	No outcome recorded
Phase 3	NCT04466618 Comparator	Apr 2021 → Dec 2022	type 2 diabetes mellitus	Adrian Vella	Completed	No outcome recorded
Phase 3	NCT04374799 Comparator	Oct 2020 → Aug 2026 overdue	heart disorder	London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's	Recruiting	No outcome recorded
Phase 3	NCT04536272 Comparator	Oct 2020 → Mar 2025	heart failure, hemorrhagic disease, respiratory failure, thrombotic disease	University Medical Center Groningen	Completed	No outcome recorded
Phase 3	NCT04532333 Comparator	Aug 2020 → May 2021	acquired aneurysmal subarachnoid hemorrhage	Changhai Hospital	Unknown	No outcome recorded
Phase 3	NCT04486508 Background	Jul 2020 → Apr 2021	COVID-19	Rajaie Cardiovascular Medical and Research Center	Completed	No outcome recorded
Phase 3	NCT04401293 Comparator	Apr 2020 → May 2021	COVID-19	Northwell Health	Completed	No outcome recorded
Phase 3	NCT02144064 Comparator	Jun 2019 → Oct 2022	pregnancy loss, recurrent, 4	Benha University	Unknown	No outcome recorded
Phase 3	NCT04297839 Comparator	Feb 2019 → Jul 2022	acute kidney injury, dialysis disequilibrium syndrome, poisoning	University of Sao Paulo General Hospital	Suspended	No outcome recorded
Phase 3	NCT03463915 Comparator	Jan 2019 → Oct 2020	interstitial cystitis	Olivia Cardenas-Trowers, M.D.	Completed	No outcome recorded
Phase 3	NCT03422419 Background	Aug 2018 → Oct 2020	portal vein thrombosis	Insel Gruppe AG, University Hospital Bern	Withdrawn	No outcome recorded
Phase 3	NCT03395639 Comparator	May 2018 → Dec 2021	heart disorder	Daiichi Sankyo	Completed	No outcome recorded
Phase 3	NCT02897037 Comparator	Nov 2016 → Jun 2017	acute myocardial infarction	Shenzhen Salubris Pharmaceuticals Co., Ltd.	Unknown	No outcome recorded
Phase 3	NCT02664155 Comparator	Oct 2016 → Nov 2021	impaired renal function disease	University Hospital of Saint-Etienne	Terminated	No outcome recorded
Phase 3	NCT02651428 Comparator	Dec 2015 → Oct 2018	chronic renal failure syndrome, prosthesis-related infectious disease	CorMedix	Completed	No outcome recorded
Phase 3	NCT02448550 Comparator	May 2015 → May 2016	—	Kaiser Permanente	Terminated	No outcome recorded
Phase 3	NCT02565147 Comparator	Dec 2014 → Jun 2016	acute myocardial infarction	The Medicines Company	Terminated	No outcome recorded
Phase 3	NCT01913483 Comparator	Sep 2013 → Mar 2016	hemorrhagic disease, peripheral arterial disease	The Medicines Company	Terminated	No outcome recorded
Phase 3	NCT01924104 Comparator	Aug 2013 → Aug 2014	—	Dr.Vandana Bansal	Unknown	No outcome recorded
Phase 3	NCT01962116 Comparator	Jun 2013 → Apr 2016	—	Centre Hospitalier Universitaire Dijon	Completed	No outcome recorded
Phase 3	NCT02091479 Comparator	Jan 2013 → Jun 2015	—	University Hospital of Saint-Etienne	Terminated	No outcome recorded
Phase 3	NCT01780987 Comparator	Jan 2013 → Sep 2014	pulmonary embolism, venous thromboembolism	Pfizer	Completed	No outcome recorded
Phase 3	NCT01935557 Comparator	Dec 2012 → Jul 2015	disseminated intravascular coagulation	Yong Seog Oh	Completed	No outcome recorded
Phase 3	NCT01651780 Comparator	Oct 2012 → Jun 2015	aortic valve stenosis	The Medicines Company	Completed	No outcome recorded
Phase 3	NCT01989091 Comparator	Jul 2012 → Oct 2014	—	Great Lakes Pharmaceuticals Inc.	Terminated	No outcome recorded
Phase 3	NCT01483872 Background	Mar 2012 → Sep 2013	—	University of California, San Diego	Terminated	No outcome recorded
Phase 3	NCT01516840 Comparator	Mar 2012 → Dec 2013	venous thromboembolism	Bayer	Completed	No outcome recorded
Phase 3	NCT01516814 Comparator	Feb 2012 → Oct 2013	pulmonary embolism	Bayer	Completed	No outcome recorded
Phase 3	NCT01352039 Comparator	Oct 2011	—	Eurofarma Laboratorios S.A.	Terminated	No outcome recorded
Phase 3	NCT01346215 Comparator	Oct → Dec 2011	chronic renal failure syndrome	Laboratório Químico Farmacêutico Bergamo Ltda.	Unknown	No outcome recorded
Phase 3	NCT01343680 Comparator	Apr 2011 → May 2012	aplastic anemia, childhood malignant neoplasm, metabolic disease	Alberta Children's Hospital	Terminated	No outcome recorded
Phase 3	NCT01166997 Comparator	Jul 2010 → Apr 2013	—	Boston Scientific Corporation	Completed	No outcome recorded
Phase 3	NCT00914472 Comparator	Apr 2010 → Mar 2011	thrombotic disease	Azidus Brasil	Unknown	No outcome recorded
Phase 3	NCT01087723 Comparator	Mar 2010 → Aug 2013	acute coronary syndrome	The Medicines Company	Completed	No outcome recorded
Phase 3	NCT00894829 Comparator	Jun 2009 → Sep 2011	cardiac valvular defect	Azidus Brasil	Completed	No outcome recorded
Phase 3	NCT00894998 Comparator	Jun → Sep 2009	—	Azidus Brasil	Completed	No outcome recorded
Phase 3	NCT00882635 Comparator	Oct 2008 → Jun 2012	acute myocardial infarction	Robert Welsh	Completed	No outcome recorded
Phase 3	NCT00718471 Comparator	Aug 2008 → Mar 2010	ST-elevation myocardial infarction	Assistance Publique - Hôpitaux de Paris	Completed	No outcome recorded
Phase 3	NCT01465503 Comparator	Jan 2008 → Dec 2012	hemorrhagic disease	Clinica Mediterranea	Completed	No outcome recorded
Phase 3	NCT05148377 Comparator	Aug 2007 → Dec 2008	—	Eurofarma Laboratorios S.A.	Completed	No outcome recorded
Phase 3	NCT00464087 Comparator	Jun 2007 → Nov 2010	acute coronary syndrome	Medstar Health Research Institute	Completed	No outcome recorded
Phase 3	NCT00451412 Comparator	Jan 2007 → Jun 2009	venous thromboembolism	Novartis	Completed	No outcome recorded
Phase 3	NCT00628680 Comparator	Jul 2006 → Jul 2008	end stage renal failure	Ash Access Technology	Unknown	No outcome recorded
Phase 3	NCT00182143 Comparator	May 2006 → Jun 2010	venous thromboembolism	McMaster University	Completed	No outcome recorded
Phase 3	NCT00311753 Comparator	Feb 2006 → Dec 2007	venous thromboembolism	Novartis Pharmaceuticals	Completed	No outcome recorded
Phase 3	NCT00238667 Comparator	Nov 2005 → May 2014	carotid artery dissection, stroke disorder, vertebral artery dissection	St George's, University of London	Completed	No outcome recorded
Phase 3	NCT00433966 Comparator	Mar 2005 → Jun 2008	myocardial infarction	Cardiovascular Research Foundation	Completed	No outcome recorded
Phase 3	NCT00079586 Comparator	Apr → Nov 2004	coronary artery intramyocardial course	The Medicines Company	Completed	No outcome recorded
Phase 3	NCT00073593 Comparator	Aug 2003 → May 2004	cardiac valvular defect, coronary artery intramyocardial course	The Medicines Company	Completed	No outcome recorded
Phase 3	NCT00637468 Background	Sep 2002 → ?	central retinal artery occlusion, stroke disorder	University Hospital Freiburg	Terminated	No outcome recorded
Phase 3	NCT00269880 Comparator	Feb → Dec 1995	—	Centocor, Inc.	Completed	No outcome recorded
Phase 3	NCT00628576 Comparator	Oct 1993 → Jun 2004	venous thromboembolism	Aalborg University Hospital	Completed	No outcome recorded
Phase 3	NCT00000472 Background	Apr 1989 → Jun 1995	coronary artery disorder, myocardial infarction, myocardial ischemia	National Heart, Lung, and Blood Institute (NHLBI)	Completed	No outcome recorded

Phase 463 trials
Phase 4	NCT07404345 Background	Mar 2026 → Mar 2028 expected	end stage renal failure	Hospital Civil de Guadalajara	Not yet recruiting	No outcome recorded
Phase 4	NCT07618988 Comparator	Aug 2024 → Dec 2025	venous thromboembolism	Ain Shams University	Completed	No outcome recorded
Phase 4	NCT06442267 Comparator	Jul 2024 → Jan 2027 expected	hemorrhagic disease, respiratory failure, thrombotic disease	Medical University of Vienna	Recruiting	No outcome recorded
Phase 4	NCT06375616 Comparator	Apr 2024 → Apr 2027 expected	infectious disease with sepsis	Shen Lei	Not yet recruiting	No outcome recorded
Phase 4	NCT05697692 Comparator	Dec 2022 → Feb 2024	—	Medical University of Vienna	Unknown	No outcome recorded
Phase 4	NCT05493163 Comparator	Oct 2022 → Mar 2026	pulmonary embolism	Faculty Hospital Kralovske Vinohrady	Completed	No outcome recorded
Phase 4	NCT05191290 Comparator	Jan → Dec 2022	—	University Medical Centre Ljubljana	Completed	No outcome recorded
Phase 4	NCT04790370 Comparator	Aug 2021 → Jul 2025 overdue	pulmonary embolism	Boston Scientific Corporation	Active not recruiting	No outcome recorded
Phase 4	NCT04635839 Comparator	Dec 2020 → Mar 2022	pregnancy disorder	University of California, Los Angeles	Completed	No outcome recorded
Phase 4	NCT04645550 Background	Nov 2020 → Dec 2023	cirrhosis of liver, portal hypertension, splenic disorder, venous thromboembolism	Northern Jiangsu People's Hospital	Completed	No outcome recorded
Phase 4	NCT04195997 Comparator	Feb → Dec 2020	—	Shanghai Zhongshan Hospital	Unknown	No outcome recorded
Phase 4	NCT04411316 Comparator	Dec 2019 → Dec 2022	post-thrombotic syndrome, venous thromboembolism	University of Toledo Health Science Campus	Withdrawn	No outcome recorded
Phase 4	NCT04185077 Comparator	Nov 2019 → Dec 2020	ST-elevation myocardial infarction	Second Xiangya Hospital of Central South University	Unknown	No outcome recorded
Phase 4	NCT04054128 Comparator	Sep 2019 → Feb 2020	end stage renal failure	Hospital General "Dr. Miguel Silva" de Morelia	Unknown	No outcome recorded
Phase 4	NCT03988842 Background	Jul 2019 → Apr 2020	acute cor pulmonale, pulmonary embolism, pulmonary embolism and infarction	Victor Tapson, MD	Terminated	No outcome recorded
Phase 4	NCT04046029 Comparator	Jul 2019 → Jul 2020	acute coronary syndrome, blood coagulation disease	The First Affiliated Hospital of Dalian Medical University	Unknown	No outcome recorded
Phase 4	NCT03965208 Comparator	May 2019 → Dec 2020	—	Legacy Health System	Unknown	No outcome recorded
Phase 4	NCT03894904 Background	Apr 2019 → Oct 2020	—	The University of Texas Health Science Center, Houston	Completed	No outcome recorded
Phase 4	NCT06807905 Comparator	Feb 2019 → Sep 2020	end stage renal failure	University Medical Centre Ljubljana	Completed	No outcome recorded
Phase 4	NCT03882775 Comparator	Jan 2019 → Jul 2020	ST-elevation myocardial infarction	The First Affiliated Hospital of Dalian Medical University	Unknown	No outcome recorded
Phase 4	NCT06646328 Comparator	Jun 2018 → Apr 2021	acute kidney injury	Fernando Sanchez	Terminated	No outcome recorded
Phase 4	NCT03539718 Comparator	May → Nov 2018	thrombotic disease	Ain Shams University	Unknown	No outcome recorded
Phase 4	NCT03318393 Comparator	Mar 2018 → Oct 2021	childhood acute lymphoblastic leukemia	University of Texas Southwestern Medical Center	Completed	No outcome recorded
Phase 4	NCT06365398 Comparator	Jan 2018 → Jun 2021	—	Xuanwu Hospital, Beijing	Completed	No outcome recorded
Phase 4	NCT03081169 Comparator	Apr 2017 → Aug 2019	traumatic brain injury, venous thromboembolism	Loyola University	Withdrawn	No outcome recorded
Phase 4	NCT03333395 Comparator	Feb → Sep 2017	—	Ain Shams University	Completed	No outcome recorded
Phase 4	NCT02787317 Comparator	May 2016 → Oct 2017	coronary artery disorder	Chinese PLA General Hospital	Unknown	No outcome recorded
Phase 4	NCT02669589 Comparator	Mar 2016 → Apr 2019	acute kidney injury	University Hospital Muenster	Completed	No outcome recorded
Phase 4	NCT02957877 Comparator	Mar 2016 → May 2018	end stage renal failure	Alice Ho Miu Ling Nethersole Hospital	Unknown	No outcome recorded
Phase 4	NCT02454491 Comparator	May 2015 → Aug 2016	ischemic disease	University Hospital of Ferrara	Completed	No outcome recorded
Phase 4	NCT02860299 Comparator	Feb 2015 → Jan 2016	acute kidney injury	Centre Hospitalier Universitaire Dijon	Completed	No outcome recorded
Phase 4	NCT02247414 Background	Sep 2014 → Sep 2017	cirrhosis of liver, hypertensive disorder, portal vein thrombosis	Yangzhou University	Completed	No outcome recorded
Phase 4	NCT02515201 Comparator	Sep 2014 → Mar 2015	prosthesis-related infectious disease	Hospital de Clinicas de Porto Alegre	Unknown	No outcome recorded
Phase 4	NCT02311231 Comparator	Jun 2014 → Mar 2017	ST-elevation myocardial infarction	Uppsala University	Completed	No outcome recorded
Phase 4	NCT02868697 Comparator	Nov 2013 → Aug 2015	—	Hamad Medical Corporation	Completed	No outcome recorded
Phase 4	NCT01930396 Comparator	Sep 2013 → Sep 2016	chronic renal failure syndrome	Christine Ribic	Completed	No outcome recorded
Phase 4	NCT02618317 Comparator	Jul 2013 → Feb 2016	chronic kidney disease	University of Sao Paulo	Completed	No outcome recorded
Phase 4	NCT01696110 Comparator	Aug 2012 → Jul 2013	acute myocardial infarction	Shenyang Northern Hospital	Completed	No outcome recorded
Phase 4	NCT02563041 Comparator	Jul 2012 → Jul 2014	prosthesis-related infectious disease	Catholic University of Pelotas	Completed	No outcome recorded
Phase 4	NCT01519518 Comparator	Feb 2012 → Dec 2013	ST-elevation myocardial infarction	Liverpool Heart and Chest Hospital NHS Foundation Trust	Completed	No outcome recorded
Phase 4	NCT01343381 Comparator	Jun → Sep 2011	coronary artery disorder	McMaster University	Completed	No outcome recorded
Phase 4	NCT01318811 Comparator	Mar 2011 → Apr 2016	acute kidney injury, heart failure	Vanderbilt University	Terminated	No outcome recorded
Phase 4	NCT02132689 Comparator	Mar 2011 → May 2015	pulmonary embolism	University Hospital Ostrava	Completed	No outcome recorded
Phase 4	NCT01956955 Comparator	Jan 2011 → Dec 2013	—	Ataturk University	Unknown	No outcome recorded
Phase 4	NCT01228292 Comparator	Jan 2011 → Jan 2012	acute kidney injury	University Hospital, Antwerp	Unknown	No outcome recorded
Phase 4	NCT01157455 Background	May 2010 → Mar 2012	coronary artery disorder	CCRF Consulting Co., Ltd.	Unknown	No outcome recorded
Phase 4	NCT01084993 Comparator	Mar 2010 → Sep 2018	coronary artery disorder	Laval University	Unknown	No outcome recorded
Phase 4	NCT00976092 Comparator	Sep 2009 → Feb 2014	myocardial infarction	German Heart Center Munich	Unknown	No outcome recorded
Phase 4	NCT01267487 Comparator	Jul 2009 → Mar 2010	—	SANE-Society of Anesthesiology	Completed	No outcome recorded
Phase 4	NCT01464671 Comparator	Jul 2009 → Sep 2014	coronary artery disorder	Stony Brook University	Terminated	No outcome recorded
Phase 4	NCT00407641 Comparator	Mar 2009 → Jan 2015	diabetes mellitus	Anemia Working Group Romania	Withdrawn	No outcome recorded
Phase 4	NCT01917799 Comparator	Jan 2009 → Nov 2013	habitual spontaneous abortion, pregnancy disorder	University of Khartoum	Unknown	No outcome recorded
Phase 4	NCT00669149 Comparator	Jun 2008 → Aug 2013	coronary artery disorder	Centre Hospitalier de PAU	Terminated	No outcome recorded
Phase 4	NCT00890214 Comparator	Sep 2007 → May 2008	acute kidney injury	Catholic University of the Sacred Heart	Completed	No outcome recorded
Phase 4	NCT00435487 Comparator	Jun 2007 → Dec 2008	intermediate coronary syndrome, myocardial infarction	Pfizer	Terminated	No outcome recorded
Phase 4	NCT00445328 Comparator	Jun 2007 → Jul 2008	venous thromboembolism	Pfizer	Terminated	No outcome recorded
Phase 4	NCT00448461 Comparator	Mar 2007 → Jun 2008	coronary artery disorder	Careggi Hospital	Completed	No outcome recorded
Phase 4	NCT01718288 Background	Nov 2006 → Mar 2011	peripheral arterial disease	Fadoi Foundation, Italy	Completed	No outcome recorded
Phase 4	NCT00277394 Comparator	Dec 2005 → May 2008	venous thromboembolism	LEO Pharma	Completed	No outcome recorded
Phase 4	NCT00262054 Comparator	Nov 2005 → Feb 2008	coronary artery disorder	German Heart Center Munich	Completed	No outcome recorded
Phase 4	NCT00790387 Comparator	Jun 2004 → Dec 2005	acute coronary syndrome	The Prince Charles Hospital	Completed	No outcome recorded
Phase 4	NCT00571259 Comparator	Sep 2003 → Jan 2010	bacterial infectious disease	Satellite Healthcare	Completed	No outcome recorded
Phase 4	NCT00796692 Comparator	Jun 2002 → Feb 2006	pulmonary embolism, thrombotic disease, venous thromboembolism	Beijing Chao Yang Hospital	Completed	No outcome recorded

Phase not applicable52 trials
—	NCT06937372 Comparator	Aug 2026 → Oct 2027 expected	venous thromboembolism	Queen Mary University of London	Not yet recruiting	No outcome recorded
—	NCT07548346 Background	Jul 2026 → Jan 2029 expected	cerebral sinovenous thrombosis	Middle East North Africa Stroke and Interventional Neurotherapies Organization	Not yet recruiting	No outcome recorded
—	NCT07618858 Comparator	Jun → Dec 2026 expected	end stage renal failure	University Medical Centre Ljubljana	Not yet recruiting	No outcome recorded
—	NCT07286409 Comparator	Jan → Dec 2026 expected	acute respiratory distress syndrome	Tanta University	Not yet recruiting	No outcome recorded
—	NCT06861374 Comparator	May 2025 → Mar 2028 expected	ST-elevation myocardial infarction	First Affiliated Hospital Xi'an Jiaotong University	Not yet recruiting	No outcome recorded
—	NCT06676085 Comparator	Nov 2024 → Dec 2027 expected	—	Beijing Chao Yang Hospital	Recruiting	No outcome recorded
—	NCT06583889 Comparator	Aug 2024 → Jan 2029 expected	cerebral sinovenous thrombosis	Beijing Tiantan Hospital	Recruiting	No outcome recorded
—	NCT06314620 Comparator	Mar 2024 → Mar 2027 expected	—	National University of Malaysia	Recruiting	No outcome recorded
—	NCT06055920 Comparator	Nov 2023 → Jul 2026 overdue	pulmonary embolism	Inari Medical	Active not recruiting	No outcome recorded
—	NCT07374978 Comparator	Jul 2023 → May 2025	pulmonary embolism	Ain Shams University	Completed	No outcome recorded
—	NCT07366372 Background	May 2023 → Nov 2024	—	Tanta University	Completed	No outcome recorded
—	NCT05707936 Comparator	Feb → Sep 2023	—	Chang Gung Memorial Hospital	Unknown	No outcome recorded
—	NCT05701917 Comparator	Jan 2023 → Jun 2026 overdue	post-thrombotic syndrome, venous thromboembolism	Inari Medical	Recruiting	No outcome recorded
—	NCT04049591 Comparator	Mar 2022 → Oct 2024 overdue	cardiovascular disorder	Population Health Research Institute	Recruiting	No outcome recorded
—	NCT05998421 Background	Mar 2022 → Mar 2023	blood coagulation disease, habitual spontaneous abortion	Jianmei Xia	Completed	No outcome recorded
—	NCT05257213 Comparator	Feb 2022 → Feb 2026 overdue	adhesions of uterus	Nadezhda Women's Health Hospital	Recruiting	No outcome recorded
—	NCT05148026 Comparator	Nov 2021 → Jul 2025	acute kidney injury, acute respiratory distress syndrome	University of Milano Bicocca	Completed	No outcome recorded
—	NCT04925167 Comparator	Jul 2021 → Dec 2023	respiratory failure	Beijing Chao Yang Hospital	Completed	No outcome recorded
—	NCT04772209 Comparator	Feb 2021 → Mar 2022	prosthesis-related infectious disease, urinary tract infection	Zonguldak Ataturk State Hospital	Completed	No outcome recorded
—	NCT04475835 Comparator	Jan 2021 → Dec 2022	ST-elevation myocardial infarction	First Affiliated Hospital Xi'an Jiaotong University	Unknown	No outcome recorded
—	NCT04394182 Background	Apr → Dec 2020	cytokine release syndrome, viral pneumonia	Fundacion GenesisCare	Suspended	No outcome recorded
—	NCT05237726 Comparator	Apr 2020 → Feb 2022	—	King Abdullah International Medical Research Center	Completed	No outcome recorded
—	NCT05914896 Comparator	Apr 2019 → Jun 2020	acute kidney injury	Umeå University	Completed	No outcome recorded
—	NCT03425448 Comparator	Apr 2019 → Oct 2020	—	King Abdullah International Medical Research Center	Unknown	No outcome recorded
—	NCT03822975 Comparator	Feb 2019 → May 2022	ST-elevation myocardial infarction	Shenyang Northern Hospital	Completed	No outcome recorded
—	NCT05953675 Comparator	Aug 2018 → Dec 2024	—	Zealand University Hospital	Unknown	No outcome recorded
—	NCT03537586 Background	Jun 2018 → Jun 2025 overdue	coronary microvascular disorder, myocardial ischemia	NYU Langone Health	Active not recruiting	No outcome recorded
—	NCT02485184 Comparator	Jul 2017 → Dec 2024	cirrhosis of liver, portal vein thrombosis	Air Force Military Medical University, China	Unknown	No outcome recorded
—	NCT03465735 Background	Jan 2017 → Aug 2019	venous thromboembolism	Mayo Clinic	Terminated	No outcome recorded
—	NCT02653092 Background	Jun 2016 → Dec 2023 overdue	hyperinsulinism, hypogonadotropic hypogonadism, infertility disorder, obesity disorder	University of Colorado, Denver	Active not recruiting	No outcome recorded
—	NCT02707263 Comparator	Mar 2016 → Apr 2017	venous thromboembolism	NYU Langone Health	Withdrawn	No outcome recorded
—	NCT02674906 Comparator	Feb 2016 → Jun 2017	—	Ziekenhuis Oost-Limburg	Completed	No outcome recorded
—	NCT02517307 Background	Feb 2016 → Jan 2021	carnitine palmitoyl transferase II deficiency, myopathic form, long chain 3-hydroxyacyl-CoA dehydrogenase deficiency, medium chain acyl-CoA dehydrogenase deficiency, mitochondrial trifunctional protein deficiency +1	Oregon Health and Science University	Completed	No outcome recorded
—	NCT02411331 Background	Mar 2015 → Jan 2017	staphylococcal infection	University Hospital, Clermont-Ferrand	Unknown	No outcome recorded
—	NCT01855516 Comparator	Sep 2013 → Dec 2015	thrombotic disease	University of Montreal Hospital Centre (CHUM)	Completed	No outcome recorded
—	NCT01520454 Background	Nov 2011 → Dec 2013	obesity disorder	Beth Israel Deaconess Medical Center	Completed	No outcome recorded
—	NCT01356615 Comparator	Mar 2011	end stage renal failure	Tehran University of Medical Sciences	Completed	No outcome recorded
—	NCT01325779 Comparator	Mar 2011 → Feb 2013	venous thromboembolism	Lisa Louwers	Withdrawn	No outcome recorded
—	NCT01070875 Comparator	Apr 2010 → Jun 2012	thrombotic disease	University of Montreal Hospital Centre (CHUM)	Completed	No outcome recorded
—	NCT00879957 Comparator	Jan 2010 → Mar 2011	respiratory distress syndrome in premature infants, thrombotic disease	The University of Texas Health Science Center at San Antonio	Withdrawn	No outcome recorded
—	NCT01229592 Comparator	Dec 2009 → Feb 2012	prosthesis-related infectious disease	Hospital General Universitario Gregorio Marañon	Terminated	No outcome recorded
—	NCT01074567 Background	Dec 2009 → Dec 2011	interstitial cystitis	Assaf-Harofeh Medical Center	Unknown	No outcome recorded
—	NCT00669721 Comparator	Mar → Jun 2008	kidney failure	IRCCS Azienda Ospedaliero-Universitaria di Bologna	Unknown	No outcome recorded
—	NCT00885300 Background	Jan → Jul 2008	—	Shiraz University of Medical Sciences	Completed	No outcome recorded
—	NCT00721136 Comparator	Sep 2007 → Aug 2010	atrial fibrillation, heart valve disorder	Johns Hopkins University	Completed	No outcome recorded
—	NCT01608906 Comparator	May 2007 → May 2014	venous thromboembolism	University of Colorado, Denver	Completed	No outcome recorded
—	NCT01044888 Background	Apr 2007 → Mar 2008	—	Yonsei University	Completed	No outcome recorded
—	NCT00473603 Background	Dec 2006 → May 2008	—	Charite University, Berlin, Germany	Completed	No outcome recorded
—	NCT00779558 Comparator	Nov 2005 → Nov 2007	thrombotic disease	Stanford University	Completed	No outcome recorded
—	NCT00184899 Background	Aug 2005 → Aug 2006	metabolic syndrome X, obesity disorder	Radboud University Medical Center	Completed	No outcome recorded
—	NCT00577096 Comparator	Oct 2001 → Jun 2004	plasma cell myeloma	University of Arkansas	Completed	No outcome recorded
—	NCT00431665 Background	Jul 1999 → Jun 2000	—	Medical University of Vienna	Completed	No outcome recorded

Phase not stated1 trial
—	NCT01049633 Background	—	type 1 diabetes mellitus	National Institute of Allergy and Infectious Diseases (NIAID)	No longer available	No outcome recorded

Press releases naming this drug 2 releases

Date	Issuer	Release
2008-07-16	Daiichi Sankyo	Approval Acquired for Additional Indication for the Selective Antithrombin Agents Novastan® HI Injection 10 mg/2mL and Slonnon® HI Injection 10 mg/2mL For the Inhibition of Thrombosis in Heparin-Induced Thrombocytopenia (HIT) Type II daiichisankyo.com ↗
2007-09-28	Daiichi Sankyo	Application Filed for Additional Indication for Selective Antithrombin Agents Novastan(R) HI Injection 10mg/2mL and Slonnon(R) HI Injection 10mg/2mL for Heparin-Induced Thrombocytopenia daiichisankyo.com ↗

Evidence & citations 50 cited values

Every value below carries the sentence it was read from. 409 sources stand behind the page.

Field	Value	Cited text
Known as	Heparin	“Bladder instillation mixture of heparin (10,000 units), 2% viscous lidocaine (10 mL), 8.4% sodium bicarbonate (15 mL of 1 mEq/mL), 0.5% bupivacaine (10 mL of 5 mg/mL) plus...” NCT03463915 ↗ 230 “standard heparin / low molecular weight heparin, hemorheological / vasodilators such as pentoxifylline / buflomedil, propionyl-L-carnitine, Defibrotide) but not prostanoids” NCT01718288 ↗ “1.35% taurolidine citrate (2H-1,2,4-thiadiazine-4,4'-methylenebis\[tetrahydro-1,1,1',1'-tetraoxide\], 4% citrate and 500 IU/ml heparin (TauroLock Hep500) (TauroPharmGmbH” NCT02868697 ↗ “If participant falls in LD heparin group, he/she will receive IV heparin 2000-3000 IU (\<60 Kg-2000 IU; 60-80 Kg-2500 IU; \>80 Kg-3000 IU) at the start of CAG” NCT05591872 ↗ “prime solution containing Ringer-Acetate 1000 ml + Mannitol 400 ml (60 g) + Sodium-Chloride 40 ml (160 mmol) and Heparin 2 ml (10 000 IU)” NCT05914896 ↗ “Heparin: Nebulized heparin has been proposed as a treatment for ARDS patients due to its anti-inflammatory and anticoagulant effects.” NCT07286409 ↗ “Standard of care could include low molecular weight heparin (LMWH) and/or VKA according to the clinical site's SOC treatment regimen” NCT03395639 ↗ “continuous infusion heparin 6 hours postoperatively (initial dose 10 iu/kg/h, dynamic regulation according to ACT 160-180s)” NCT04241380 ↗ “intra-vesical: DMSO 50% in 50 cc water for injection 10 cc heparin 5000 IU hydrocortisone 100 mg bupivacaine 0.125%” NCT01074567 ↗ “Heparin may be used as an alternative to bivalirudin at the discretion of the interventional cardiologist.” NCT03537586 ↗ “Heparin, low molecular weight heparin, or coumadin could be used if the patient was intolerant to aspirin.” NCT00790842 ↗ “either low molecular weight heparin (LMWH) or unfractionated heparin (UFH)” NCT02735707 ↗ “Intravesical lidocaine, heparin, sodium bicarb, Kenalog, gentamicin” NCT05658874 ↗ “Anticoagulation therapy includes heparin and warfarin.” NCT02485184 ↗ “changed to Heparin at the discretion of the MRP.” NCT06662253 ↗ “Anticoagulation will be heparin only.” NCT04411316 ↗ “the drug heparin of porcine origin” NCT01034488 ↗ “* Heparin 10,000 units” NCT00317070 ↗ “Warfarin/heparin” NCT02798471 ↗ “Heparin” NCT03483207 ↗ “Heparin” NCT03465735 ↗ NCT04505774 ↗ NCT04401176 ↗ NCT00001713 ↗ NCT06707480 ↗ NCT00361348 ↗ NCT01325779 ↗ NCT02271126 ↗ NCT06381661 ↗ NCT02970032 ↗ NCT01087723 ↗ NCT03882775 ↗ NCT04273607 ↗ NCT00196417 ↗ NCT01084993 ↗ NCT00932100 ↗ NCT06080074 ↗ NCT00188773 ↗ NCT01924104 ↗ NCT02040818 ↗ NCT06583889 ↗ NCT01651923 ↗ NCT00587444 ↗ NCT01204333 ↗ NCT05634057 ↗ NCT01989091 ↗ NCT03425448 ↗ NCT04355273 ↗ NCT03333395 ↗ NCT04372589 ↗ NCT04466618 ↗ NCT01823393 ↗ NCT00657228 ↗ NCT02653092 ↗ NCT02144064 ↗ NCT04195997 ↗ NCT06807905 ↗ NCT02159287 ↗ NCT01520454 ↗ NCT00196469 ↗ NCT04536272 ↗ NCT04496362 ↗ NCT04355728 ↗ NCT00628680 ↗ NCT00508924 ↗ NCT04532333 ↗ NCT01214772 ↗ NCT07074821 ↗ NCT01049633 ↗ NCT01343680 ↗ NCT01382888 ↗ NCT06676085 ↗ NCT05329155 ↗ NCT05223244 ↗ NCT02897037 ↗ NCT02529774 ↗ NCT06314620 ↗ NCT02311231 ↗ NCT05209841 ↗ NCT00184899 ↗ NCT00079586 ↗ NCT01652638 ↗ NCT04042324 ↗ NCT03752437 ↗ NCT00828776 ↗ NCT03822975 ↗ NCT04227678 ↗ NCT05886998 ↗ NCT02664155 ↗ NCT01917799 ↗ NCT01729559 ↗ NCT04772209 ↗ NCT03114722 ↗ NCT01483872 ↗ NCT07404345 ↗ NCT02812355 ↗ NCT03422419 ↗ NCT03516656 ↗ NCT02493504 ↗ NCT04419493 ↗ NCT00004694 ↗ NCT04511923 ↗ NCT00269880 ↗ NCT00657475 ↗ NCT02036255 ↗ NCT02645240 ↗ NCT03867851 ↗ NCT00373451 ↗ NCT04185077 ↗ NCT05788913 ↗ NCT01454869 ↗ NCT04842292 ↗ NCT05414305 ↗ NCT01163097 ↗ NCT00669149 ↗ NCT00905216 ↗ NCT04046029 ↗ NCT00073593 ↗ NCT02651428 ↗ NCT01343381 ↗ NCT01464671 ↗ NCT04764396 ↗ NCT01267487 ↗ NCT01234285 ↗ NCT00256542 ↗ NCT02477072 ↗ NCT00789308 ↗ NCT01260519 ↗ NCT02497326 ↗ NCT04397510 ↗ NCT02986594 ↗ NCT00976092 ↗ NCT00890214 ↗ NCT01048177 ↗ NCT02515201 ↗ NCT00879957 ↗ NCT05737121 ↗ NCT03350737 ↗ NCT06822426 ↗ NCT02990403 ↗ NCT02591199 ↗ NCT06365398 ↗ NCT02707263 ↗ NCT00407641 ↗ NCT02687256 ↗ NCT00571259 ↗ NCT01696110 ↗ NCT02227329 ↗ NCT04790370 ↗ NCT04374799 ↗ NCT00329433 ↗ NCT05188339 ↗ NCT04397289 ↗ NCT06453876 ↗ NCT02435732 ↗ NCT05788900 ↗ NCT04297839 ↗ NCT04723563 ↗ NCT00378781 ↗ NCT07162064 ↗ NCT02246270 ↗ NCT00277394 ↗ NCT00271401 ↗ NCT00060554 ↗ NCT00614679 ↗ NCT07366372 ↗ NCT01794767 ↗ NCT06714864 ↗ NCT04054128 ↗ NCT05953675 ↗ NCT02787317 ↗ NCT01862978 ↗ NCT03894904 ↗ NCT00701623 ↗ NCT02618317 ↗ NCT01157455 ↗ NCT01070875 ↗ NCT00914472 ↗ NCT01363193 ↗ NCT01229592 ↗ NCT00311753 ↗ NCT02675647 ↗ NCT02674906 ↗ NCT04600141 ↗ NCT05602129 ↗ NCT05998421 ↗ NCT04475835 ↗ NCT05707936 ↗ NCT04655586 ↗ NCT04061798 ↗ NCT00000472 ↗ NCT01855516 ↗ NCT01044888 ↗ NCT05257213 ↗ NCT01598883 ↗ NCT00494156 ↗ NCT03302195 ↗ NCT00445211 ↗ NCT06549842 ↗ NCT02181985 ↗ NCT00637468 ↗ NCT02454491 ↗ NCT00448461 ↗ NCT02563041 ↗ NCT03006562 ↗ NCT04490239 ↗ NCT07618988 ↗ NCT01976988 ↗ NCT01935557 ↗ NCT03672006 ↗ NCT05029596 ↗ NCT00473603 ↗ NCT05178550 ↗ NCT03633994 ↗ NCT04367831 ↗ NCT01694459 ↗ NCT06112262 ↗ NCT01356329 ↗ NCT01608906 ↗ NCT02565147 ↗ NCT00721136 ↗ NCT02365285 ↗ NCT02517307 ↗ NCT00431665 ↗ NCT00885300 ↗ NCT02940444 ↗ NCT01394458 ↗ NCT00790439 ↗ NCT01356615 ↗ NCT02669589 ↗ NCT03081169 ↗
Known as	Actparin	“The purpose of this study is to investigate clinical non-inferiority, pharmacodynamic effect and safety of Actparin® (heparin sodium - Laboratório Químico Farmacêutico Bergamo...” NCT01346215 ↗
Known as	Alimax	“Clinical Efficacy of Product Alimax ® (Sodic Heparin) in Treatment of Burns: Comparative Study of Raw Materials Between Two Suppliers” NCT00701623 ↗
Known as	APP Sodium heparin = Sodium heparin (App Pharmaceuticals)	“APP Sodium heparin = Sodium heparin (App Pharmaceuticals)” NCT01652638 ↗
Known as	Calciparine	“Otherwise unfractionated heparin (Calciparine®, Héparine Sodique Choay®) subcutaneously or intravenous with an anti-Xa target between 0.5 and 0.7 IU/mL for 14 days” NCT04344756 ↗
Known as	clexan	“clexan” NCT00928213 ↗ 1 “Clexan” NCT03963336 ↗
Known as	Enoxalow	“The hypothesis of this trial is that the test drug (Enoxalow® - T) pharmacodynamics parameters are similar to the comparator drug (Clexane® - C) in healthy subjects following...” NCT01692171 ↗ 1 “Enoxalow (Heparin, Low-Molecular-Weight) - Blau Farmacêutica S/A.” NCT01692158 ↗
Known as	Fibrilin TM	“Every three day lock using Heparin(Fibrilin TM) 3ml in all the lumen of the Catheter” NCT01229592 ↗
Known as	Fibrillin	“Catheters will be sealed with 3 mL of Fibrillin Ⓡ (heparin 20UI/mL)” NCT05209841 ↗
Known as	HEP-IV	ClinicalTrials.gov intervention name — accepted as the source's own label NCT02966080 ↗
Known as	Hepalean	“Hepalean Heparin” NCT01343381 ↗ 1 NCT00848796 ↗
Known as	Hepamax-S = Sodium heparin (Blau Farmacêutica S/A)	“Hepamax-S = Sodium heparin (Blau Farmacêutica S/A)” NCT01652638 ↗
Known as	Heparin calcium	ClinicalTrials.gov intervention name — accepted as the source's own label NCT01051778 ↗
Known as	Heparin Leo	ClinicalTrials.gov intervention name — accepted as the source's own label NCT00848796 ↗
Known as	Heparin sodic	“Heparin sodic - Cristália” NCT00828776 ↗
Known as	Heparin Sodium	“The objective of this clinical, randomized, crossover, is to assess the pharmacodynamic profile of the drug Heparin Sodium from swine (intravenously), manufactured and marketed...” NCT01651923 ↗ 31 “The purpose of this study is to determine if the combination product (URG101) is safe and effective versus its individual components (Heparin Sodium and Lidocaine...” NCT02591199 ↗ “Both products are marketed as heparin sodium extracted from porcine intestinal mucosa. Heparin Leo is 1000 international units (British Pharmacopeia) per ml. while Hepalean is...” PMID 10182116 ↗ Jun 1998 “Full Dose Tenecteplase (TNK-tPA) Together With Heparin Sodium, Full Dose Tenecteplase With Enoxaparin, Half Dose Tenecteplase Together With Abciximab and Heparin Sodium in...” NCT02181985 ↗ “Current guidelines recommended either heparin sodium (unfractionated heparin) or low-molecular-weight heparin (LMWH) for those patients at high risk of deep vein thrombosis (DVT).” PMID 28523161 ↗ Apr 2017 “Commercially available/market approved anticoagulation medication including but not limited to: Heparin Sodium, Coumadin, Rivaroxaban, Apixaban, etc.” NCT06055920 ↗ “Heparin 25000 IU in 5ml (5 ampoules of Heparin Sodium 5000 I.U/ML, Nile company for Pharmaceuticals and Chemical Industries-A.R.E.)” NCT03333395 ↗ “The investigators are investigating the tolerability of Heparin Sodium (porcine) administered topically via a nasal spray.” NCT04490239 ↗ “Heparin sodium (50,000 USPU) in alkalinized buffer, administered as a single dose via intravesical instillation” NCT05737121 ↗ “Heparin Sodium, 1000 Units/mL Injectable Solution 1” NCT04054128 ↗ “Heparin sodium (Generic, 5000 IU/ml ampoules)” NCT05886998 ↗ NCT04530578 ↗ NCT05701917 ↗ NCT04743011 ↗ NCT03707418 ↗ NCT00894829 ↗ NCT03113708 ↗ NCT00912483 ↗ NCT00894959 ↗ NCT02654561 ↗ NCT06646328 ↗ NCT00894985 ↗ NCT00894998 ↗ NCT00934167 ↗ NCT01352039 ↗ NCT03539718 ↗ NCT01346215 ↗ NCT05749393 ↗ NCT05697692 ↗ NCT04767113 ↗ NCT03306836 ↗ NCT02206087 ↗
Known as	Heparin Sodium (porcine)	“The investigators are investigating the tolerability of Heparin Sodium (porcine) administered topically via a nasal spray.” NCT04490239 ↗
Known as	Heparin Sodium - APP Pharmaceuticals	“Heparin Sodium - APP Pharmaceuticals” NCT01352039 ↗
Known as	heparin sodium - blausiegel	“heparin sodium - blausiegel” NCT00894985 ↗
Known as	Heparin Sodium - Eurofarma	“Heparin Sodium - Eurofarma” NCT01352039 ↗
Known as	Heparin sodium APP	“Heparin sodium APP 5.000 USP” NCT00894959 ↗ 2 “Heparin sodium APP 5.000 USP” NCT00894829 ↗ “heparin sodium - APP” NCT00894985 ↗
Known as	Heparin sodium Blausiegel 1	“Heparin sodium Blausiegel 1 5.000 UI” NCT00894959 ↗
Known as	Heparin Sodium Injection	“the drug is Heparin Sodium Injection 2ml:12500 Units per bottle” NCT06365398 ↗
Known as	Heparin Sodium Injection, USP	“Comparator Drug: Heparin Sodium Injection, USP, injectable solution - 5,000 IU/ 0.5 mL; Fresenius Kabi Lake Zurich.” NCT05788913 ↗ 1 “Comparator Drug: Heparin Sodium Injection, USP, injectable solution - 5,000 IU/mL; Fresenius Kabi Lake Zurich.” NCT05788900 ↗
Known as	Heparin Sodium USP	“Supplier The test article (Heparin Sodium USP) will be obtained from appropriate commercial sources.” NCT04490239 ↗
Known as	Heparin sulfate	ClinicalTrials.gov intervention name — accepted as the source's own label NCT00779558 ↗
Known as	heparin sulphate	“heparin sulphate 40,000 IU (4 cc of 10,000 units/cc), lidocaine 2% 16 ml, Sodium bicarbonate 8.4% 4 ml and Kenalog 40 mg (1cc) to reach a total fluid volume of 25 ml will be...” NCT02870738 ↗
Known as	Heparin, Low-Molecular-Weight	ClinicalTrials.gov intervention name — accepted as the source's own label NCT00577096 ↗
Known as	Heparin-Natrium-5000-ratiopharm	“Heparin-Natrium-5000-ratiopharm (unfractionated heparin)” NCT04419493 ↗
Known as	Heparine	ClinicalTrials.gov intervention name — accepted as the source's own label NCT02132689 ↗ 1 NCT02411331 ↗
Known as	HeparinTM	“Group B:HeparinTM (Unfractionated Heparin)” NCT01356329 ↗
Known as	Héparine Sodique Choay	“Otherwise unfractionated heparin (Calciparine®, Héparine Sodique Choay®) subcutaneously or intravenous with an anti-Xa target between 0.5 and 0.7 IU/mL for 14 days” NCT04344756 ↗
Known as	Liquaemin	ClinicalTrials.gov intervention name — accepted as the source's own label NCT05148377 ↗
Known as	Liquemin	“unfractionated heparin UFH (Liquemin®, Roche).” NCT00890214 ↗
Known as	Liquemine	“heparin - Liquemine (Roche)” NCT00828776 ↗
Known as	LMWH	“A daily dose of 40 mg of low-molecular-weight heparin (LMWH) subcutaneously was given to the patients.” NCT06484634 ↗ 1 “Low molecular weight heparin (LMWH)” NCT06937372 ↗
Known as	Low molecular weight heparin	“Heparin, low molecular weight heparin, or coumadin could be used if the patient was intolerant to aspirin.” NCT00790842 ↗ 7 NCT05604859 ↗ NCT04394182 ↗ NCT03120715 ↗ NCT06484634 ↗ NCT02247414 ↗ NCT06937372 ↗ NCT04645550 ↗
Known as	Porcine sodium heparin	“Experimental Drug: Porcine sodium heparin, injectable solution - 5,000 IU/ 0.25 mL; Blau Farmacêutica S/A.” NCT05788913 ↗ 1 “Experimental Drug: Porcine sodium heparin, injectable solution - 5,000 IU/mL; Blau Farmacêutica S/A.” NCT05788900 ↗
Known as	PPC	“PPC Heparin” NCT01343381 ↗
Known as	Sodic Heparin	“Clinical Efficacy of Product Alimax ® (Sodic Heparin) in Treatment of Burns: Comparative Study of Raw Materials Between Two Suppliers” NCT00701623 ↗
Known as	sodium heparin	“Heparin (sodium heparin 5000 IU/ml) was administered as a bolus dose (50 IU/kg body weight) intravenously into the pre-dialyzer arterial line of the extracorporeal blood...” NCT01356615 ↗ 3 “The intention of this work is to verify the effectiveness and safety of sodium heparin in the treatment of burns of the skin.” NCT00701623 ↗ NCT03125187 ↗ NCT00427310 ↗
Known as	Sodium heparin FK	“The participants will be hospitalized one day to receive the Sodium heparin UQ experimental medication or Sodium heparin FK comparator medication.” NCT03125187 ↗
Known as	Sodium heparin UQ	“The participants will be hospitalized one day to receive the Sodium heparin UQ experimental medication or Sodium heparin FK comparator medication.” NCT03125187 ↗
Known as	UFH	“The patients will be allocated by randomisation in equal proportions to the two treatment groups receiving UFH (70 units/kg prior to the procedure) or bivalirudin (bolus of...” NCT01519518 ↗ 48 “AIMS: Although a 140 U/kg dose of unfractionated heparin (UFH) was comparable with bivalirudin in terms of net clinical outcome in the Intracoronary Stenting and Antithrombotic...” PMID 20805113 ↗ Aug 2010 “Systemic infusion of unfractionated heparin (UFH) is the standard anticoagulation technique for continuous renal replacement therapy (CRRT) during extracorporeal membrane...” PMID 31045918 ↗ Mar 2020 “This study is designed to assess the incidence of abnormal partial thromboplastin time in patients receiving unfractionated heparin (UFH) 5000 U 2 times a day versus 3 times a day.” NCT01070875 ↗ “Unfractionated heparin (UFH) administered intravenously with a nomogram targeting an aPTT of 1.5-2.5 times the control as per institutional therapeutic target for treatment of VTE” NCT04409834 ↗ “therapeutic-dose low molecular-weight heparin (LMWH) or unfractionated heparin (UFH) administered daily for up to 14 days or until hospital discharge, whichever occurs first.” NCT05848713 ↗ “Standard anticoagulation therapy consisting of intravenous unfractionated heparin (UFH) or subcutaneous low-molecular-weight heparin (LMWH) during the acute phase” NCT07548346 ↗ “Patients are randomized before diagnostic catheterization to receive intravenously either 100IU/Kg or 50 IU/Kg of unfractionated heparin (UFH) in a 1:1 ratio.” NCT02570243 ↗ “Although unfractionated heparin (UFH) reduces RAO, it may increase bleeding risk; thus, the optimal balance between efficacy and safety remains uncertain.” PMID 41985829 ↗ Apr 2026 “Every patient will have 2 HD procedures with PES-PVP membrane in a randomized order: 1 with unfractionated heparin (UFH) and 1 with 8% trisodium citrate.” NCT04139525 ↗ “Participants were randomly allocated to the standard dose of UFH (5,000 units subcutaneously every 12 hours) or the gestational age-based dose of UFH” PMID 38743958 ↗ May 2024 “The experimental group was required to be given an intravenous injection of 100 U/kg of UFH within 10 minutes after randomization” NCT07361783 ↗ “Patients randomized to the Control group will receive unfractionated heparn (UFH) before and during the procedure.” NCT01465503 ↗ “activated partial thromboplastin time-adjusted intravenous unfractionated heparin (UFH) followed by warfarin” PMID 25717286 ↗ Jan 2015 “We identified eight studies (581 participants) that compared citrate with unfractionated heparin (UFH).” PMID 33314078 ↗ Dec 2020 “Unfractionated heparin (UFH) Commenced, administered, and monitored according to local hospital policy” NCT04372589 ↗ “intravenous unfractionated heparin (UFH) so as to reach an anti-Xa activity between 0.3 and 0.7 IU/mL” NCT02091479 ↗ “Unfractionated heparin (UFH) is a sulfated polysaccharide extracted from porcine intestinal mucosa” NCT03426982 ↗ “unfractionated heparin (UFH), low-molecular-weight heparins (LMWHs), fondaparinux, and danaparoid” PMID 22315264 ↗ Feb 2012 “However, the optimal dose of unfractionated heparin (UFH) for elective PCI is currently unclear.” PMID 41443541 ↗ Dec 2025 “Inhaled nebulised unfractionated heparin (UFH) has a strong scientific and biological rationale” PMID 33377218 ↗ Jan 2021 “pretreatment with unfractionated heparin (UFH) in patients with STEMI referred to primary PCI.” PMID 41910504 ↗ Mar 2026 “Unfractionated heparin (UFH): a common anticoagulant used during hemodialysis treatments.” NCT04042324 ↗ “desired attributes of unfractionated heparin (UFH) and low-molecular-weight heparin:” PMID 20368520 ↗ Apr 2010 “treatment dose unfractionated heparin (UFH) in ARDS from a different viral family” NCT04401293 ↗ “Intravenous unfractionated heparin (UFH) infusion within 6 hours of EVT” NCT04121611 ↗ “low molecular weight heparin (LMWH) versus unfractionated heparin (UFH)” NCT04444700 ↗ “unfractionated heparin (UFH) 5000 U 2 times a day versus 3 times a day” NCT01855516 ↗ “standard doses of Unfractionated Heparin (UFH) vs. high doses of UFH.” NCT04561648 ↗ “unfractionated heparin (UFH) and low molecular weight heparin (LMWH)” NCT00182403 ↗ “Unfractionated heparin (UFH) has known anti-inflammatory actions.” NCT02501434 ↗ “Fragmin (Dalteparin) LMWH verus Unfractionated Heparin (UFH)” NCT00182364 ↗ “one unfractionated heparin (UFH) group (70-100 IU/kg bolus)” PMID 20226548 ↗ Mar 2010 “unfractionated heparin (UFH) for HD anticoagulation” PMID 38189593 ↗ Jan 2024 “intravenous continuous infusion of heparin (IV UFH)” NCT02707263 ↗ “Standard heparin (UFH) versus certoparin (LMWH)” NCT00196417 ↗ “Unfractionated heparin (UFH) 1400u each nostril” NCT05204550 ↗ “unfractionated heparin UFH (Liquemin®, Roche).” NCT00890214 ↗ “Unfractionated Heparin (UFH) 5000 U q8 hours” NCT05237726 ↗ “intravenous unfractionated heparin (IV UFH)” NCT01956955 ↗ “Nebulised unfractionated heparin (UFH)” NCT04545541 ↗ “Drug: Unfractionated Heparin (UFH)” NCT01780987 ↗ “unfractionated heparin (UFH)” NCT03000673 ↗ “unfractionated heparin (UFH)” NCT02144064 ↗ “Unfractionated heparin (UFH)” NCT01513200 ↗ “unfractionated heparin (UFH)” NCT00981409 ↗ “unfractionated heparin (UFH)” NCT00911157 ↗ “UFH (unfractionated heparin)” NCT00718471 ↗ “Unfractionated Heparin (UFH)” NCT06517563 ↗
Known as	unfractionated heparin	“This study is designed to assess the incidence of abnormal partial thromboplastin time in patients receiving unfractionated heparin (UFH) 5000 U 2 times a day versus 3 times a day.” NCT01070875 ↗ 134 “Current guidelines recommended either heparin sodium (unfractionated heparin) or low-molecular-weight heparin (LMWH) for those patients at high risk of deep vein thrombosis (DVT).” PMID 28523161 ↗ Apr 2017 “Unfractionated heparin is the most negatively charged biological molecule known, heparin has a strong ability to interfere with the functioning of positively charged molecules.” NCT04313790 ↗ “therapeutic-dose low molecular-weight heparin (LMWH) or unfractionated heparin (UFH) administered daily for up to 14 days or until hospital discharge, whichever occurs first.” NCT05848713 ↗ “Participants' catheters were locked between hemodialysis sessions with the C-MB-P lock solution or sterile saline containing 5000 units of unfractionated heparin (control).” PMID 21200319 ↗ Apr 2011 “Sodium bicarbonate is as effective as classic unfractionated heparin in preventing catheter lumen thrombosis with a comparable incidence of catheter-related complications.” PMID 37823971 ↗ Oct 2023 “Before randomization, all patients are treated with intravenous unfractionated heparin (to a target aPTT of 70-90 s) or subcutaneous LMWH (the full therapeutic dose).” NCT05493163 ↗ “Standard anticoagulation therapy consisting of intravenous unfractionated heparin (UFH) or subcutaneous low-molecular-weight heparin (LMWH) during the acute phase” NCT07548346 ↗ “Adult patients scheduled for elective cardiac or thoracic surgery received desirudin 15 mg SC twice daily or unfractionated heparin 5000 units SC thrice daily.” PMID 21794899 ↗ Jul 2011 “Safety profile of tinzaparin versus subcutaneous unfractionated heparin in elderly patients with impaired renal function treated for acute deep vein thrombosis” PMID 21477846 ↗ Apr 2011 “Although unfractionated heparin (UFH) reduces RAO, it may increase bleeding risk; thus, the optimal balance between efficacy and safety remains uncertain.” PMID 41985829 ↗ Apr 2026 “Unfractionated heparin was administered subcutaneously as an initial dose of 333 U/kg, followed by a fixed dose of 250 U/kg every 12 hours (n = 345).” PMID 16926353 ↗ Aug 2006 “OPG and RANKL Plasma Level After Administration of Unfractionated Heparin (UFH) and Low-Molecular-Weight Heparin (LMWH) in Hemodialysis” NCT00669721 ↗ “Patients received a bolus dose of unfractionated heparin of either 300 IU kg of TBW or 340 IU kg of IBW before onset of CPB.” PMID 29521662 ↗ Aug 2018 “The choice of low molecular weight heparin (LMWH) versus unfractionated heparin (UFH) will be at the clinician's discretion.” NCT04362085 ↗ “Unfractionated heparin dosed to target activated partial thromboplastin time (aPTT) between 1.5 - 2.0 times the normal value” NCT04485429 ↗ “Unfractionated heparin (UFH) Commenced, administered, and monitored according to local hospital policy” NCT04372589 ↗ “unfractionated heparin or low-molecular weight heparin with transition to an oral vitamin K antagonist” NCT03178864 ↗ “intravenous unfractionated heparin (UFH) so as to reach an anti-Xa activity between 0.3 and 0.7 IU/mL” NCT02091479 ↗ “25,000 units of unfractionated heparin nebulized 4 times daily for the duration of hospitalization” NCT04723563 ↗ “However, the optimal dose of unfractionated heparin (UFH) for elective PCI is currently unclear.” PMID 41443541 ↗ Dec 2025 “Unfractionated heparin (UFH): a common anticoagulant used during hemodialysis treatments.” NCT04042324 ↗ “Patients in control group will receive Unfractionated heparin treatment” NCT01980316 ↗ “low molecular weight heparin (LMWH) versus unfractionated heparin (UFH)” NCT04444700 ↗ “one unfractionated heparin (UFH) group (70-100 IU/kg bolus)” PMID 20226548 ↗ Mar 2010 “Heparin-Natrium-5000-ratiopharm (unfractionated heparin)” NCT04419493 ↗ “unfractionated heparin (UFH) for HD anticoagulation” PMID 38189593 ↗ Jan 2024 “unfractionated heparin UFH (Liquemin®, Roche).” NCT00890214 ↗ “Group B:HeparinTM (Unfractionated Heparin)” NCT01356329 ↗ “citrate with unfractionated heparin (UFH)” PMID 33314078 ↗ Dec 2020 “Drug: unfractionated Heparin” NCT03822975 ↗ “Unfractionated Heparin (UFH)” NCT06517563 ↗ “unfractionated heparin” NCT01260519 ↗ “Unfractionated Heparin” NCT02501434 ↗ “unfractionated heparin” NCT01363193 ↗ “Unfractionated heparin” NCT04401293 ↗ NCT06861374 ↗ NCT03854266 ↗ NCT05247424 ↗ NCT00238667 ↗ NCT01166997 ↗ NCT04561648 ↗ NCT01651780 ↗ NCT01662908 ↗ NCT00317395 ↗ NCT00628576 ↗ NCT05237726 ↗ NCT01773083 ↗ NCT03426982 ↗ NCT01513200 ↗ NCT04121611 ↗ NCT02860299 ↗ NCT04925167 ↗ NCT06375616 ↗ NCT02957877 ↗ NCT00433966 ↗ NCT01648036 ↗ NCT00451412 ↗ NCT04139525 ↗ NCT04635241 ↗ NCT05191290 ↗ NCT00911157 ↗ NCT02135770 ↗ NCT00882635 ↗ NCT04406389 ↗ NCT04861922 ↗ NCT00911300 ↗ NCT07361783 ↗ NCT02448550 ↗ NCT00796692 ↗ NCT01519518 ↗ NCT04635839 ↗ NCT04528888 ↗ NCT06174961 ↗ NCT05204550 ↗ NCT05555641 ↗ NCT00445328 ↗ NCT04486508 ↗ NCT05959252 ↗ NCT01956955 ↗ NCT01962116 ↗ NCT00182364 ↗ NCT01930396 ↗ NCT04466670 ↗ NCT00262054 ↗ NCT00133731 ↗ NCT01913483 ↗ NCT00790387 ↗ NCT04394377 ↗ NCT06276010 ↗ NCT05184101 ↗ NCT03965208 ↗ NCT06275555 ↗ NCT00735280 ↗ NCT02501434 ↗ NCT03772613 ↗ NCT04545541 ↗ NCT00182143 ↗ NCT06753786 ↗ NCT00435487 ↗ NCT04409834 ↗ NCT07609771 ↗ NCT01318811 ↗ NCT00718471 ↗ NCT02098993 ↗ NCT06442267 ↗ NCT00253396 ↗ NCT00253851 ↗ NCT04487990 ↗ NCT03000673 ↗ NCT03988842 ↗ NCT01228292 ↗ NCT00464087 ↗ NCT00981409 ↗ NCT01516814 ↗ NCT01516840 ↗ NCT03465085 ↗ NCT00439855 ↗ NCT02570243 ↗ NCT00818753 ↗ NCT07618858 ↗ NCT03318393 ↗ NCT01839578 ↗ NCT01465503 ↗ NCT01634438 ↗ NCT01780987 ↗ NCT05148026 ↗ NCT05255848 ↗ NCT00543400 ↗ NCT03664180 ↗ NCT07374978 ↗ NCT03378466 ↗ NCT00715455 ↗ NCT05226442 ↗ NCT04344756 ↗
Known as	Unfractionated Heparin, LEO laboratories Ltd, MA #PL 0043/0041R	“Unfractionated Heparin, LEO laboratories Ltd, MA #PL 0043/0041R” NCT01228292 ↗
Known as	Unfractioned heparin	“Unfractioned heparin” NCT01823393 ↗
Action	Inhibit	“Heparin also have an anti-inflammatory effect through downregulates nuclear factor kappa B and tumor necrosis factor alpha.” NCT02135770 ↗
Modality	Other / unclassified	“unfractionated heparin (UFH)” NCT00182143 ↗
Route	Intravenous	“All patients then received intravenous heparin.” NCT00000472 ↗