Heparin
Regulatory milestones approvals, filings & regulatory actions · 8 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | HEPARIN SODIUM 25,000 UNITS IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER | — | 1989-06-23 | fda.gov ↗ |
| Label expansions (3) | US (FDA) | HEPARIN SODIUM | — | 1983-12-19 – 1986-04-11 | fda.gov ↗ |
| Label expansion | US (FDA) | HEPARIN SODIUM 25,000 UNITS AND DEXTROSE 5% IN PLASTIC CONTAINER | — | 1985-07-09 | fda.gov ↗ |
| Label expansions (2) | US (FDA) | HEPARIN LOCK FLUSH | — | 1981-05-15 – 1985-05-21 | fda.gov ↗ |
| Approved | US (FDA) | HEPARIN SODIUM | — | 1939-02-09 | fda.gov ↗ |
Trials 105 · started per year
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 05 trials | ||||||
| Phase 0 | NCT06112262 | Dec 2023 → Sep 2025 overdue | — | Basma Rabiey | Not yet recruiting | No outcome recorded |
| Phase 0 | NCT05178550 | Dec 2021 → Jan 2022 | — | Novo Nordisk A/S | Completed | No outcome recorded |
| Phase 0 | NCT04490239 | Oct → Nov 2020 | COVID-19 | Joshua Sharp | Completed | No outcome recorded |
| Phase 0 | NCT02246270 | Nov 2017 → Dec 2025 | urinary tract infection | University of Oklahoma | Completed | No outcome recorded |
| Phase 0 | NCT02970032 | Nov 2016 → Sep 2017 | pulmonary embolism, venous thromboembolism | University of Utah | Completed | No outcome recorded |
| Phase 110 trials | ||||||
| Phase 1 | NCT05788913 | Jun 2023 | — | Blau Farmaceutica S.A. | Unknown | No outcome recorded |
| Phase 1 | NCT05788900 | Jun 2023 | — | Blau Farmaceutica S.A. | Unknown | No outcome recorded |
| Phase 1 | NCT03125187 | Feb 2021 | — | Uniao Quimica | Suspended | No outcome recorded |
| Phase 1 | NCT02435732 | Dec 2020 → May 2021 | kidney failure | University of Wisconsin, Madison | Unknown | No outcome recorded |
| Phase 1 | NCT02271126 | Sep 2014 → Sep 2016 | — | Policlinico Hospital | Completed | No outcome recorded |
| Phase 1 | NCT01651923 | Feb → Apr 2013 | — | Azidus Brasil | Unknown | No outcome recorded |
| Phase 1 | NCT01652638 | Feb → Apr 2013 | — | Azidus Brasil | Unknown | No outcome recorded |
| Phase 1 | NCT01598883 | Jun 2012 → Dec 2014 | — | Massachusetts General Hospital | Completed | No outcome recorded |
| Phase 1 | NCT01163097 | Jul 2010 → Jan 2011 | mucositis | Swedish Orphan Biovitrum | Completed | No outcome recorded |
| Phase 1 | NCT00361348 | Dec 2005 → Jul 2006 | — | Swedish Orphan Biovitrum | Completed | No outcome recorded |
| Phase 1/23 trials | ||||||
| Phase 1/2 | NCT04511923 | Dec 2020 → Dec 2021 | COVID-19, acute lung injury, acute respiratory distress syndrome | University College Hospital Galway | Completed | No outcome recorded |
| Phase 1/2 | NCT04397289 | Feb 2018 → Mar 2021 | cirrhosis of liver, hemorrhagic disease, portal hypertension, thrombotic disease | First Affiliated Hospital Xi'an Jiaotong University | Completed | No outcome recorded |
| Phase 1/2 | NCT02940444 | Jun 2016 → Jun 2018 | venous thromboembolism | West China Hospital | Unknown | No outcome recorded |
| Phase 211 trials | ||||||
| Phase 2 | NCT06381661 | May 2026 → Jun 2028 expected | infectious disease with sepsis | Assistance Publique - Hôpitaux de Paris | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT06080074 | Apr 2025 → Sep 2027 expected | cardiogenic shock, cardiomyopathy, congenital heart disease, heart failure | Stanford University | Recruiting | No outcome recorded |
| Phase 2 | NCT05737121 | May 2023 → Jun 2026 overdue | interstitial cystitis | Vaneltix Pharma, Inc. | Recruiting | No outcome recorded |
| Phase 2 | NCT07074821 | Mar 2023 → Feb 2024 | — | Oman Ministry of Health | Completed | No outcome recorded |
| Phase 2 | NCT04842292 | May → Sep 2021 | COVID-19 | Brittany Bissell | Terminated | No outcome recorded Stop: Enrollment |
| Phase 2 | NCT03633994 | Aug 2018 → Dec 2019 | urinary tract infection | The Christ Hospital | Unknown | No outcome recorded |
| Phase 2 | NCT02591199 | Sep 2015 → May 2018 | interstitial cystitis | Urigen | Terminated | No outcome recorded Stop: Business |
| Phase 2 | NCT01048177 | Dec 2012 → Jun 2014 | vulvodynia | Scripps Health | Withdrawn | No outcome recorded |
| Phase 2 | NCT00317070 | Apr 2006 → Feb 2009 | interstitial cystitis | Nova Scotia Health Authority | Terminated | No outcome recorded Stop: Enrollment |
| Phase 2 | NCT00256542 | Jan → Sep 2006 | interstitial cystitis, pelvis syndrome | Urigen | Completed | No outcome recorded |
| Phase 2 | NCT00060554 | Apr 2003 → ? | coronary artery disorder, myocardial infarction | Schering-Plough | Withdrawn | No outcome recorded |
| Phase 2/35 trials | ||||||
| Phase 2/3 | NCT04273607 | Sep 2022 → Dec 2026 expected | — | Damian Ratano | Recruiting | No outcome recorded |
| Phase 2/3 | NCT04372589 | May 2020 → May 2021 | COVID-19, pneumonia | University of Manitoba | Completed | Mixed |
| Phase 2/3 | NCT02040818 | Nov 2013 → Jan 2017 | — | University of California, San Diego | Withdrawn | No outcome recorded Stop: Enrollment |
| Phase 2/3 | NCT01034488 | Aug 2010 → Dec 2011 | — | Azidus Brasil | Unknown | No outcome recorded |
| Phase 2/3 | NCT00701623 | Jun 2008 | — | Azidus Brasil | Withdrawn | No outcome recorded |
| Phase 319 trials · 2 met primary · 1 missed | ||||||
| Phase 3 | NCT07162064 | Aug 2025 → Jan 2026 | ischemic stroke | Xiang Luo | Completed | No outcome recorded |
| Phase 3 | NCT05886998 | Jun 2023 → Jun 2024 | acute lung injury | Ain Shams University | Completed | No outcome recorded |
| Phase 3 | NCT04600141 | Nov 2020 → Oct 2021 | COVID-19 | University of Sao Paulo | Completed | No outcome recorded |
| Phase 3 | NCT02654561 | Apr 2018 → Dec 2024 | disseminated intravascular coagulation, infectious disease with sepsis | China Medical University, China | Unknown | No outcome recorded |
| Phase 3 | NCT02798471 | Mar 2017 → May 2022 | pulmonary embolism, venous thromboembolism | Daiichi Sankyo | Completed | No outcome recorded |
| Phase 3 | NCT02735707 | Apr 2016 → Feb 2026 overdue | pneumonia | UMC Utrecht | Recruiting | Mixed |
| Phase 3 | NCT02036255 | May 2015 → Jul 2017 | infectious disease | University Hospital Brussels | Completed | Met primary |
| Phase 3 | NCT01976988 | Sep 2013 → May 2015 | venous thromboembolism | Cedars-Sinai Medical Center | Completed | Missed primary |
| Phase 3 | NCT01454869 | Feb → Jun 2012 | — | Tehran University of Medical Sciences | Withdrawn | No outcome recorded Stop: Business |
| Phase 3 | NCT00912483 | May → Nov 2010 | venous thromboembolism | Azidus Brasil | Withdrawn | No outcome recorded |
| Phase 3 | NCT01356329 | Oct 2009 → Aug 2016 | female reproductive system neoplasm | National Guard Health Affairs | Suspended | No outcome recorded Stop: Enrollment |
| Phase 3 | NCT00894959 | Jul → Sep 2009 | cardiac valvular defect | Azidus Brasil | Completed | No outcome recorded |
| Phase 3 | NCT00905216 | Jun → Sep 2009 | — | Azidus Brasil | Unknown | No outcome recorded |
| Phase 3 | NCT00894985 | Jun → Sep 2009 | cardiac valvular defect | Azidus Brasil | Completed | No outcome recorded |
| Phase 3 | NCT01260519 | Jul 2008 → Oct 2010 | — | Prince Sultan Cardiac Center, Adult Cardiology Department. | Completed | No outcome recorded |
| Phase 3 | NCT00587444 | Jun 2001 → Oct 2007 | — | Mayo Clinic | Completed | No outcome recorded |
| Phase 3 | NCT02181985 | May 2000 → Apr 2001 | myocardial infarction | Boehringer Ingelheim | Completed | No outcome recorded |
| Phase 3 | NCT00271401 | Jul 1996 → Sep 1997 | — | Centocor, Inc. | Completed | Met primary |
| Phase 3 | NCT00427310 | Mar 1984 → Sep 1989 | colorectal cancer | NSABP Foundation Inc | Completed | No outcome recorded |
| Phase 429 trials · 1 met primary · 3 missed | ||||||
| Phase 4 | NCT06714864 | Jul 2025 → Jul 2028 expected | prosthesis-related infectious disease | CorMedix Therapeutics | Recruiting | No outcome recorded |
| Phase 4 | NCT04723563 | Feb → Aug 2021 | COVID-19, viral pneumonia | Frederick Health | Completed | No outcome recorded |
| Phase 4 | NCT04505774 | Sep 2020 → Aug 2023 | COVID-19 | Matthew Neal MD | Completed | Missed primary |
| Phase 4 | NCT04397510 | Jun 2020 → Dec 2021 | COVID-19, acute lung injury, acute respiratory distress syndrome | Frederick Health | Terminated | No outcome recorded Stop: Enrollment |
| Phase 4 | NCT04530578 | Jun → Oct 2020 | COVID-19, pneumonia | Clinica San Camilo, Argentina | Unknown | No outcome recorded |
| Phase 4 | NCT04367831 | May 2020 → May 2021 | COVID-19, thrombotic disease, venous thromboembolism | Columbia University | Completed | No outcome recorded |
| Phase 4 | NCT04061798 | Mar 2020 → Apr 2024 | abdominal aortic aneurysm | Dijklander Ziekenhuis | Terminated | No outcome recorded |
| Phase 4 | NCT03752437 | Oct 2019 → Sep 2021 | — | Astes | Completed | No outcome recorded |
| Phase 4 | NCT04496362 | Oct 2018 → Feb 2025 overdue | respiratory failure | Baylor Research Institute | Active not recruiting | No outcome recorded |
| Phase 4 | NCT03006562 | Jul 2017 → Nov 2019 | lymphocele, prostate cancer, pulmonary embolism, venous thromboembolism | Johns Hopkins University | Terminated | Missed primary |
| Phase 4 | NCT03113708 | Apr → May 2017 | hemorrhagic disease, hyperheparinemia | Adiyaman University Research Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT02812355 | Jan 2017 → Jan 2019 | ischemic disease | Azienda Ospedaliera di Lecco | Unknown | No outcome recorded |
| Phase 4 | NCT02986594 | Nov 2016 → Oct 2019 | thrombophilia | Shanghai First Maternity and Infant Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT02675647 | Dec 2015 → Dec 2016 | morbid obesity | University Hospital, Strasbourg, France | Completed | No outcome recorded |
| Phase 4 | NCT02645240 | Oct 2015 → Jul 2017 | acute intestinal ischemia | Mansoura University | Completed | No outcome recorded |
| Phase 4 | NCT02990403 | Oct 2014 → Jun 2017 | pregnancy loss, recurrent, 4 | Shanghai First Maternity and Infant Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT01862978 | May 2013 → May 2015 | ischemic stroke | University Hospital, Martin | Unknown | No outcome recorded |
| Phase 4 | NCT01823393 | Jan 2013 → Oct 2016 | aortic valve stenosis | University Hospital, Montpellier | Terminated | Met primary |
| Phase 4 | NCT01794767 | Jan 2013 → Aug 2014 | phlebitis | University of Florence | Suspended | No outcome recorded Stop: Enrollment |
| Phase 4 | NCT01729559 | Nov 2012 → Sep 2014 | pulmonary embolism, venous thromboembolism | Scripps Health | Completed | No outcome recorded |
| Phase 4 | NCT05223244 | Oct 2011 → Apr 2019 | interstitial cystitis | Endeavor Health | Completed | No outcome recorded |
| Phase 4 | NCT02493504 | Jan 2011 → Apr 2012 | arteriovenous hemangioma/malformation | Fatemeh Hoseinzadegan | Completed | No outcome recorded |
| Phase 4 | NCT01694459 | Jan 2010 → Dec 2012 | intermediate coronary syndrome, myocardial infarction | San Filippo Neri General Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT01214772 | May → Sep 2009 | pregnancy disorder, thrombophilia | Yazd Medical University | Completed | No outcome recorded |
| Phase 4 | NCT00657475 | Jun 2008 → Feb 2013 | — | University Hospital, Bordeaux | Completed | No outcome recorded |
| Phase 4 | NCT00373451 | Jul 2006 → May 2011 | coronary artery disorder, myocardial infarction | German Heart Center Munich | Completed | Missed primary |
| Phase 4 | NCT00188773 | Jan 2004 → Aug 2007 | metabolic syndrome X | University Health Network, Toronto | Completed | No outcome recorded |
| Phase 4 | NCT00196469 | Dec 2003 → Mar 2007 | hemorrhagic disease | University Medicine Greifswald | Unknown | No outcome recorded |
| Phase 4 | NCT00196417 | Jan 2003 → Nov 2005 | heparin-induced thrombocytopenia | University Medicine Greifswald | Unknown | No outcome recorded |
| Phase not applicable22 trials · 1 missed | ||||||
| — | NCT06549842 | Aug 2024 → Feb 2026 | arterial occlusion, hemorrhagic disease | Regional Hospital of Scranton | Completed | No outcome recorded |
| — | NCT05634057 | Jan 2024 → Dec 2025 overdue | infectious disease with sepsis | Chen Ying | Recruiting | No outcome recorded |
| — | NCT05749393 | Apr 2023 → Mar 2024 | brain aneurysm | The First Affiliated Hospital with Nanjing Medical University | Unknown | No outcome recorded |
| — | NCT05329155 | Jul 2022 → Aug 2023 | ST-elevation myocardial infarction | Renmin Hospital of Wuhan University | Completed | No outcome recorded |
| — | NCT05209841 | Apr 2022 → Jul 2026 overdue | — | Consorci Sanitari de l'Alt Penedès i Garraf | Recruiting | No outcome recorded |
| — | NCT04764396 | Mar → Apr 2021 | pancreatic neoplasm | University of Michigan | Terminated | No outcome recorded Stop: Business |
| — | NCT04767113 | Mar 2021 → Aug 2022 | venous thromboembolism | Guangdong Provincial People's Hospital | Completed | Missed primary |
| — | NCT04241380 | Feb 2020 → Oct 2021 | congenital total pulmonary venous return anomaly | Guangdong Provincial People's Hospital | Unknown | No outcome recorded |
| — | NCT04227678 | Dec 2019 → Dec 2026 expected | familial lipoprotein lipase deficiency | University of Sherbrooke | Recruiting | No outcome recorded |
| — | NCT03483207 | Apr 2018 → Dec 2019 | isolated mesenteric vein thrombosis | Assiut University | Unknown | No outcome recorded |
| — | NCT04355273 | Jan → Feb 2018 | hyperheparinemia | Yangzhou University | Completed | No outcome recorded |
| — | NCT03306836 | Sep 2016 → Sep 2020 | arteriovenous hemangioma/malformation, brain aneurysm | Beijing Tiantan Hospital | Unknown | No outcome recorded |
| — | NCT02477072 | Sep 2015 → Jan 2016 | peripheral vascular disease | University of Montreal Hospital Centre (CHUM) | Completed | No outcome recorded |
| — | NCT03302195 | Aug 2015 → Dec 2024 overdue | obesity disorder | Laval University | Recruiting | No outcome recorded |
| — | NCT02497326 | Apr → Dec 2015 | — | King Edward Medical University | Unknown | No outcome recorded |
| — | NCT03350737 | Feb 2013 → Dec 2019 | intermediate coronary syndrome | Clinical Centre of Serbia | Completed | No outcome recorded |
| — | NCT01394458 | Aug 2011 → Nov 2013 | bacterial infectious disease, prosthesis-related infectious disease | University of Manitoba | Completed | No outcome recorded |
| — | NCT01363193 | Jul 2011 → Dec 2014 | atrial fibrillation, intermediate coronary syndrome, morbid obesity, venous thromboembolism | Nazareth Hospital | Unknown | No outcome recorded |
| — | NCT00657228 | Dec 2009 → Dec 2010 | anaphylaxis | University of Missouri, Kansas City | Withdrawn | No outcome recorded |
| — | NCT00494156 | Jul 2003 → Jul 2008 | arterial disorder | C. Clay Cothren, MD | Withdrawn | No outcome recorded Stop: Enrollment |
| — | NCT00004694 | Jan 1994 → Sep 1998 | angioedema | University of Iowa | Completed | No outcome recorded |
| — | NCT00378781 | — | cancer | M.D. Anderson Cancer Center | Withdrawn | No outcome recorded |
| Phase not stated1 trial | ||||||
| — | NCT06707480 | — | — | CorMedix | No longer available | No outcome recorded |
| Comparator or background therapy158 trials | ||||||
| Phase 0 | NCT05029596 Comparator | Feb 2020 → Mar 2023 | cancer | University of Texas Southwestern Medical Center | Completed | No outcome recorded |
| Phase 0 | NCT03516656 Comparator | Mar 2018 → Jun 2019 | pulmonary embolism, venous thromboembolism | University of Utah | Completed | No outcome recorded |
| Phase 1 | NCT07759167 Background | Sep 2026 → Apr 2027 expected | end stage renal failure | Regeneron Pharmaceuticals | Recruiting | No outcome recorded |
| Phase 1 | NCT03707418 Comparator | Apr → Jun 2021 | — | Johns Hopkins University | Withdrawn | No outcome recorded Stop: Business |
| Phase 1 | NCT04419493 Background | Jun 2020 → Jun 2021 | — | Boehringer Ingelheim | Completed | Met primary |
| Show all 158 trials opens the full record — a long page | ||||||
News releases announcing trial results or a regulatory action · 7
| Date | Issuer | Release |
|---|---|---|
| 2024-06-06 | CorMedix | Regulatory CORMEDIX INC. ANNOUNCES CMS GRANTS PASS-THROUGH STATUS TO DEFENCATH cormedix.com ↗
today announced that the Center for Medicare & Medicaid Services (CMS) has determined that DefenCath® qualifies for pass-through status under the hospital Out-Patient Prospective Payment System (OPPS). |
| 2024-04-19 | CorMedix | Regulatory CORMEDIX INC. ANNOUNCES CMS GRANTS TDAPA TO DEFENCATHDefenCath® (taurolidine and heparin)IMPORTANT SAFETY INFORMATION cormedix.com ↗
CMS determination of TDAPA eligibility for DefenCath is a critical step toward ensuring this innovative preventative drug product is available for patients in the outpatient dialysis setting. |
| 2023-11-15 | CorMedix | Regulatory CORMEDIX INC. ANNOUNCES FDA APPROVAL OF DEFENCATH® TO REDUCE THE INCIDENCE OF CATHETER-RELATED BLOODSTREAM INFECTIONS IN ADULT HEMODIALYSIS PATIENTS cormedix.com ↗
DefenCath is the first and only FDA-approved antimicrobial CLS in the U.S. and was shown to reduce the risk of CRBSIs by up to 71% in a Phase 3 clinical study. |
| 2023-05-16 | CorMedix | Regulatory CORMEDIX INC. ANNOUNCES RESUBMISSION OF NEW DRUG APPLICATION FOR DEFENCATH cormedix.com ↗
today announced that the New Drug Application for DefenCath was resubmitted to the U.S. Food and Drug Administration, and the submission has been acknowledged as received for processing. |
| 2021-11-16 | Rockwell Medical Technologies, Inc. | Results Rockwell Medical Study Demonstrates No Drug-drug Interaction Between Ferric Pyrophosphate Citrate and Unfractionated Heparin rockwellmed.com ↗ |
| 2021-03-01 | CorMedix | Regulatory CORMEDIX RECEIVES COMPLETE RESPONSE LETTER FROM FDA FOR DEFENCATH™ CATHETER LOCK SOLUTION cormedix.com ↗
CorMedix Inc. (NASDAQ: CRMD), a biopharmaceutical company focused on developing and commercializing therapeutic products for the prevention and treatment of infectious and inflammatory disease, announced today that the US Food and Drug Administration (FDA) cannot approve the New Drug Application (NDA) for DefenCath™ (taurolidine/heparin catheter lock solution) in its present form. |
| 2015-03-30 | Janssen Research & Development, LLC | Results New Study Shows Reduced Hospital Admissions and Costs for Deep Vein Thrombosis Patients Treated with XARELTO® Compared to Traditional Therapy, With No Difference in Subsequent Hospital Visits jnj.com ↗
A 27 percent reduction in hospital admissions when patients were treated with XARELTO® instead of LMWH and warfarin (p<0.001). |
All press releases naming this drug 11 releases
Evidence & citations 41 cited values
Every value below carries the sentence it was read from. 273 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Heparin | “Bladder instillation mixture of heparin (10,000 units), 2% viscous lidocaine (10 mL), 8.4% sodium bicarbonate (15 mL of 1 mEq/mL), 0.5% bupivacaine (10 mL of 5 mg/mL) plus...” NCT03463915 ↗231“standard heparin / low molecular weight heparin, hemorheological / vasodilators such as pentoxifylline / buflomedil, propionyl-L-carnitine, Defibrotide) but not prostanoids” NCT01718288 ↗ “1.35% taurolidine citrate (2H-1,2,4-thiadiazine-4,4'-methylenebis\[tetrahydro-1,1,1',1'-tetraoxide\], 4% citrate and 500 IU/ml heparin (TauroLock Hep500) (TauroPharmGmbH” NCT02868697 ↗ “If participant falls in LD heparin group, he/she will receive IV heparin 2000-3000 IU (\<60 Kg-2000 IU; 60-80 Kg-2500 IU; \>80 Kg-3000 IU) at the start of CAG” NCT05591872 ↗ “prime solution containing Ringer-Acetate 1000 ml + Mannitol 400 ml (60 g) + Sodium-Chloride 40 ml (160 mmol) and Heparin 2 ml (10 000 IU)” NCT05914896 ↗ “Heparin: Nebulized heparin has been proposed as a treatment for ARDS patients due to its anti-inflammatory and anticoagulant effects.” NCT07286409 ↗ “Standard of care could include low molecular weight heparin (LMWH) and/or VKA according to the clinical site's SOC treatment regimen” NCT03395639 ↗ “continuous infusion heparin 6 hours postoperatively (initial dose 10 iu/kg/h, dynamic regulation according to ACT 160-180s)” NCT04241380 ↗ “intra-vesical: DMSO 50% in 50 cc water for injection 10 cc heparin 5000 IU hydrocortisone 100 mg bupivacaine 0.125%” NCT01074567 ↗ “Heparin may be used as an alternative to bivalirudin at the discretion of the interventional cardiologist.” NCT03537586 ↗ “Heparin, low molecular weight heparin, or coumadin could be used if the patient was intolerant to aspirin.” NCT00790842 ↗ |
| Known as | Actparin | “The purpose of this study is to investigate clinical non-inferiority, pharmacodynamic effect and safety of Actparin® (heparin sodium - Laboratório Químico Farmacêutico Bergamo...” NCT01346215 ↗ |
| Known as | Alimax | “Clinical Efficacy of Product Alimax ® (Sodic Heparin) in Treatment of Burns: Comparative Study of Raw Materials Between Two Suppliers” NCT00701623 ↗ |
| Known as | APP Sodium heparin = Sodium heparin (App Pharmaceuticals) | “APP Sodium heparin = Sodium heparin (App Pharmaceuticals)” NCT01652638 ↗ |
| Known as | Fibrilin TM | “Every three day lock using Heparin(Fibrilin TM) 3ml in all the lumen of the Catheter” NCT01229592 ↗ |
| Known as | Fibrillin | “Catheters will be sealed with 3 mL of Fibrillin Ⓡ (heparin 20UI/mL)” NCT05209841 ↗ |
| Known as | Hepalean | “Hepalean Heparin” NCT01343381 ↗ |
| Known as | Hepamax-S = Sodium heparin (Blau Farmacêutica S/A) | “Hepamax-S = Sodium heparin (Blau Farmacêutica S/A)” NCT01652638 ↗ |
| Known as | Heparin calcium | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01051778 ↗ |
| Known as | Heparin sodic | “Heparin sodic - Cristália” NCT00828776 ↗ |
| Known as | Heparin Sodium | “The objective of this clinical, randomized, crossover, is to assess the pharmacodynamic profile of the drug Heparin Sodium from swine (intravenously), manufactured and marketed...” NCT01651923 ↗30“The purpose of this study is to determine if the combination product (URG101) is safe and effective versus its individual components (Heparin Sodium and Lidocaine...” NCT02591199 ↗ “Full Dose Tenecteplase (TNK-tPA) Together With Heparin Sodium, Full Dose Tenecteplase With Enoxaparin, Half Dose Tenecteplase Together With Abciximab and Heparin Sodium in...” NCT02181985 ↗ “Current guidelines recommended either heparin sodium (unfractionated heparin) or low-molecular-weight heparin (LMWH) for those patients at high risk of deep vein thrombosis (DVT).” PMID 28523161 ↗ Apr 2017 “Commercially available/market approved anticoagulation medication including but not limited to: Heparin Sodium, Coumadin, Rivaroxaban, Apixaban, etc.” NCT06055920 ↗ “Heparin 25000 IU in 5ml (5 ampoules of Heparin Sodium 5000 I.U/ML, Nile company for Pharmaceuticals and Chemical Industries-A.R.E.)” NCT03333395 ↗ “The investigators are investigating the tolerability of Heparin Sodium (porcine) administered topically via a nasal spray.” NCT04490239 ↗ “Heparin sodium (50,000 USPU) in alkalinized buffer, administered as a single dose via intravesical instillation” NCT05737121 ↗ “Heparin Sodium, 1000 Units/mL Injectable Solution 1” NCT04054128 ↗ “Heparin sodium (Generic, 5000 IU/ml ampoules)” NCT05886998 ↗ |
| Known as | Heparin Sodium (porcine) | “The investigators are investigating the tolerability of Heparin Sodium (porcine) administered topically via a nasal spray.” NCT04490239 ↗ |
| Known as | Heparin Sodium - APP Pharmaceuticals | “Heparin Sodium - APP Pharmaceuticals” NCT01352039 ↗ |
| Known as | heparin sodium - blausiegel | “heparin sodium - blausiegel” NCT00894985 ↗ |
| Known as | Heparin Sodium - Eurofarma | “Heparin Sodium - Eurofarma” NCT01352039 ↗ |
| Known as | Heparin sodium APP | “Heparin sodium APP 5.000 USP” NCT00894959 ↗ |
| Known as | Heparin sodium Blausiegel 1 | “Heparin sodium Blausiegel 1 5.000 UI” NCT00894959 ↗ |
| Known as | Heparin Sodium Injection | “the drug is Heparin Sodium Injection 2ml:12500 Units per bottle” NCT06365398 ↗ |
| Known as | Heparin Sodium Injection, USP | “Comparator Drug: Heparin Sodium Injection, USP, injectable solution - 5,000 IU/ 0.5 mL; Fresenius Kabi Lake Zurich.” NCT05788913 ↗1“Comparator Drug: Heparin Sodium Injection, USP, injectable solution - 5,000 IU/mL; Fresenius Kabi Lake Zurich.” NCT05788900 ↗ |
| Known as | Heparin Sodium USP | “Supplier The test article (Heparin Sodium USP) will be obtained from appropriate commercial sources.” NCT04490239 ↗ |
| Known as | Heparin sulfate | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00779558 ↗ |
| Known as | heparin sulphate | “heparin sulphate 40,000 IU (4 cc of 10,000 units/cc), lidocaine 2% 16 ml, Sodium bicarbonate 8.4% 4 ml and Kenalog 40 mg (1cc) to reach a total fluid volume of 25 ml will be...” NCT02870738 ↗ |
| Known as | Heparin, Low-Molecular-Weight | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00577096 ↗ |
| Known as | Heparin-Natrium-5000-ratiopharm | “Heparin-Natrium-5000-ratiopharm (unfractionated heparin)” NCT04419493 ↗ |
| Known as | Heparine | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02132689 ↗ |
| Known as | HeparinTM | “Group B:HeparinTM (Unfractionated Heparin)” NCT01356329 ↗ |
| Known as | Liquaemin | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05148377 ↗ |
| Known as | Liquemin | “unfractionated heparin UFH (Liquemin®, Roche).” NCT00890214 ↗ |
| Known as | Liquemine | “heparin - Liquemine (Roche)” NCT00828776 ↗ |
| Known as | Porcine sodium heparin | “Experimental Drug: Porcine sodium heparin, injectable solution - 5,000 IU/ 0.25 mL; Blau Farmacêutica S/A.” NCT05788913 ↗1“Experimental Drug: Porcine sodium heparin, injectable solution - 5,000 IU/mL; Blau Farmacêutica S/A.” NCT05788900 ↗ |
| Known as | PPC | “PPC Heparin” NCT01343381 ↗ |
| Known as | Sodic Heparin | “Clinical Efficacy of Product Alimax ® (Sodic Heparin) in Treatment of Burns: Comparative Study of Raw Materials Between Two Suppliers” NCT00701623 ↗ |
| Known as | sodium heparin | “Heparin (sodium heparin 5000 IU/ml) was administered as a bolus dose (50 IU/kg body weight) intravenously into the pre-dialyzer arterial line of the extracorporeal blood...” NCT01356615 ↗3“The intention of this work is to verify the effectiveness and safety of sodium heparin in the treatment of burns of the skin.” NCT00701623 ↗ |
| Known as | Sodium heparin FK | “The participants will be hospitalized one day to receive the Sodium heparin UQ experimental medication or Sodium heparin FK comparator medication.” NCT03125187 ↗ |
| Known as | Sodium heparin UQ | “The participants will be hospitalized one day to receive the Sodium heparin UQ experimental medication or Sodium heparin FK comparator medication.” NCT03125187 ↗ |
| Known as | UFH | “This study is designed to assess the incidence of abnormal partial thromboplastin time in patients receiving unfractionated heparin (UFH) 5000 U 2 times a day versus 3 times a day.” NCT01070875 ↗11“Although unfractionated heparin (UFH) reduces RAO, it may increase bleeding risk; thus, the optimal balance between efficacy and safety remains uncertain.” PMID 41985829 ↗ Apr 2026 “Unfractionated heparin (UFH) Commenced, administered, and monitored according to local hospital policy” NCT04372589 ↗ “Unfractionated heparin (UFH): a common anticoagulant used during hemodialysis treatments.” NCT04042324 ↗ “unfractionated heparin (UFH) 5000 U 2 times a day versus 3 times a day” NCT01855516 ↗ “one unfractionated heparin (UFH) group (70-100 IU/kg bolus)” PMID 20226548 ↗ Mar 2010 “intravenous continuous infusion of heparin (IV UFH)” NCT02707263 ↗ “unfractionated heparin (UFH) for HD anticoagulation” PMID 38189593 ↗ Jan 2024 “Standard heparin (UFH) versus certoparin (LMWH)” NCT00196417 ↗ “unfractionated heparin UFH (Liquemin®, Roche).” NCT00890214 ↗ “citrate with unfractionated heparin (UFH)” PMID 33314078 ↗ Dec 2020 |
| Known as | unfractionated heparin | “This study is designed to assess the incidence of abnormal partial thromboplastin time in patients receiving unfractionated heparin (UFH) 5000 U 2 times a day versus 3 times a day.” NCT01070875 ↗19“Current guidelines recommended either heparin sodium (unfractionated heparin) or low-molecular-weight heparin (LMWH) for those patients at high risk of deep vein thrombosis (DVT).” PMID 28523161 ↗ Apr 2017 “Participants' catheters were locked between hemodialysis sessions with the C-MB-P lock solution or sterile saline containing 5000 units of unfractionated heparin (control).” PMID 21200319 ↗ Apr 2011 “Sodium bicarbonate is as effective as classic unfractionated heparin in preventing catheter lumen thrombosis with a comparable incidence of catheter-related complications.” PMID 37823971 ↗ Oct 2023 “Adult patients scheduled for elective cardiac or thoracic surgery received desirudin 15 mg SC twice daily or unfractionated heparin 5000 units SC thrice daily.” PMID 21794899 ↗ Jul 2011 “Safety profile of tinzaparin versus subcutaneous unfractionated heparin in elderly patients with impaired renal function treated for acute deep vein thrombosis” PMID 21477846 ↗ Apr 2011 “Although unfractionated heparin (UFH) reduces RAO, it may increase bleeding risk; thus, the optimal balance between efficacy and safety remains uncertain.” PMID 41985829 ↗ Apr 2026 “Patients received a bolus dose of unfractionated heparin of either 300 IU kg of TBW or 340 IU kg of IBW before onset of CPB.” PMID 29521662 ↗ Aug 2018 “Unfractionated heparin (UFH) Commenced, administered, and monitored according to local hospital policy” NCT04372589 ↗ “25,000 units of unfractionated heparin nebulized 4 times daily for the duration of hospitalization” NCT04723563 ↗ “Unfractionated heparin (UFH): a common anticoagulant used during hemodialysis treatments.” NCT04042324 ↗ |
| Known as | Unfractioned heparin | “Unfractioned heparin” NCT01823393 ↗ |
| Action | Inhibit | “Burn analgesia by heparin is caused by inhibition of pro-inflammatory products” NCT02497326 ↗ |
| Modality | Other / unclassified | “full dose unfractionated heparin (UFH)” PMID 21477846 ↗ Apr 2011 |
| Route | Intravenous | “All patients then received intravenous heparin.” NCT00000472 ↗ |