Continuous Heparin Infusion to Prevent Catheter-related Thrombosis
Summary
Catheter-related thrombosis could impair blood flow in the vein, block the central venous catheter, induce catheter-related infection or venous thromboembolism in the deep veins or pulmonary vessels, which furthermore progress into the post-thrombotic syndrome. Researches using echogenic mass as the primary outcome could miss those premature thrombi which might not be seen on traditional ultrasonography but may be detected by Duplex and Doppler ultrasound with vessel compression. Moreover, studies indicated that some thrombus developed after the catheter removal. Removal of the catheter is not the endpoint of thrombus detection. This study is designed to determine the preventive effects of continuous heparin infusion on real-world central venous catheter-related thrombosis in infants after cardiac surgery.
Timeline
- Start
- 2021-03-01
- Primary completion
- 2022-08-31
- Completion
- 2022-08-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Heparin | Other / unclassified | 0.5 iu/kg | Intravenous |
| Subject | Heparin | Other / unclassified | 1 iu/kg | Intravenous |
| Subject | Heparin | Other / unclassified | 10 iu/kg | Intravenous |
| Subject | Heparin | Other / unclassified | 15 iu/kg | Intravenous |