drugset

drugset / Trial / NCT00361348

Palifermin DDI (Drug Drug Interaction)

NCT00361348 ↗

Phase 1 Completed 45 enrolled Swedish Orphan Biovitrum

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to determine if Paliferim interacts with Heparin.

Timeline

Start: 2005-12
Primary completion: 2006-07
Completion: 2006-07

Publications

Yang BB, Gillespie B, Smith B, Smith W, Lissmats A, Rudebeck M, Kullenberg T, Olsson B. Pharmacokinetic and pharmacodynamic interactions between palifermin and heparin. J Clin Pharmacol. 2015 Oct;55(10):1109-18. doi: 10.1002/jcph.516. Epub 2015 May 28.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Heparin	Other / unclassified	—	Intravenous
Subject	Palifermin	Protein / enzyme biologic	60 ug/kg	Intravenous

Indications

No indication recorded.