drugset / Trial / NCT03431675

Ciprofloxacin for the Prevention of Meningococcal Meningitis 2018

NCT03431675

RandomizedParallel-groupOpen-labelPrevention

Summary

The trial is an interventional, cluster-randomized trial to assess the impact of oral ciprofloxacin for household and community contacts of meningitis cases on the incidence of meningitis during an epidemic. The trial contains a nested sub-study ("resistance study") to assess the effect of a single dose of ciprofloxacin on the prevalence of fluoroquinolone-resistant enterobacteriaceae in the study area.

Timeline

Start
2019-03-01
Primary completion
2019-06-30
Completion
2019-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ciprofloxacin Small molecule 75 mg Oral
Comparator Ciprofloxacin Small molecule 100 mg Oral
Comparator Ciprofloxacin Small molecule 125 mg Oral
Comparator Ciprofloxacin Small molecule 250 mg Oral
Comparator Ciprofloxacin Small molecule 500 mg Oral