drugset / Trial / NCT03431675
Ciprofloxacin for the Prevention of Meningococcal Meningitis 2018
RandomizedParallel-groupOpen-labelPrevention
Summary
The trial is an interventional, cluster-randomized trial to assess the impact of oral ciprofloxacin for household and community contacts of meningitis cases on the incidence of meningitis during an epidemic. The trial contains a nested sub-study ("resistance study") to assess the effect of a single dose of ciprofloxacin on the prevalence of fluoroquinolone-resistant enterobacteriaceae in the study area.
Timeline
- Start
- 2019-03-01
- Primary completion
- 2019-06-30
- Completion
- 2019-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ciprofloxacin | Small molecule | 75 mg | Oral |
| Comparator | Ciprofloxacin | Small molecule | 100 mg | Oral |
| Comparator | Ciprofloxacin | Small molecule | 125 mg | Oral |
| Comparator | Ciprofloxacin | Small molecule | 250 mg | Oral |
| Comparator | Ciprofloxacin | Small molecule | 500 mg | Oral |