drugset / Trial / NCT03435718
Efficacy of Oxfendazole in the Treatment of Trichuris Trichiura Infection in Adults
Phase 2
Not yet recruiting
250 enrolled
Oxfendazole Development Group
Universidad Peruana Cayetano Heredia · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The main objective of this study is to provide data on the efficacy profile of different doses of oxfendazole when used in Trichuris trichiura infection. The drug will be also be examined for efficacy against other common nematodes encountered in man (Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus). The study will also provide data on the safety and tolerability of the oxfendazole in patients.
Timeline
- Start
- 2024-07
- Primary completion
- 2026-07
- Completion
- 2026-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Albendazole | Small molecule | 400 mg/kg | Oral |
| Subject | Oxfendazole | Small molecule | 6 mg/kg | Oral |
| Subject | Oxfendazole | Small molecule | 15 mg/kg | Oral |
| Subject | Oxfendazole | Small molecule | 30 mg/kg | Oral |