A Phase Ⅰb Study of Remimazolam Tosylate in Healthy Volunteers

Phase 1 Completed 8 enrolled Jiangsu HengRui Medicine Co., Ltd.

RandomizedCrossoverDouble-blindTreatment

Summary

The purpose of this study is to evaluate the Pharmacokinetics/Pharmacodynamics and safety of Remimazolam Tosylate in healthy volunteers after loading/maintenance dose regimen.

Timeline

Start: 2014-07-23
Primary completion: 2014-08-16
Completion: 2014-08-16

Publications

Chen X, Sang N, Song K, Zhong W, Wang H, Jiang J, Huang Y, Hu P. Psychomotor Recovery Following Remimazolam-induced Sedation and the Effectiveness of Flumazenil as an Antidote. Clin Ther. 2020 Apr;42(4):614-624. doi: 10.1016/j.clinthera.2020.02.006. Epub 2020 Mar 13.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Remimazolam	Small molecule	1.5 mg/kg	Intravenous

Indications

No indication recorded.