The Effect of Intravenous Acetaminophen on Post-Operative Pain After Craniotomy

Summary

The purpose of the study is to determine the efficacy of IV acetaminophen when administered to neurosurgical patients at the beginning and end of their surgery. If the result is improved pain control with less opioid consumption postoperatively, then those patients may also experience less opioid related side effects such as nausea/vomiting, pruritus, and sedation. While numerous other studies have failed to show a benefit of IV acetaminophen after neurosurgical procedures, we are studying the administration of 1 g in two doses over the course of the operation.

Timeline

Start

2014-05-01

Primary completion

2017-10-01

Completion

2017-11-01

Drugs

Indications

No indication recorded.