drugset / Trial / NCT03464942
Stereotactic Radiation and Immunotherapy in Patients With Advanced Triple Negative Breast Cancer
Phase 2
Completed
54 enrolled
Peter MacCallum Cancer Centre, Australia
Trans Tasman Radiation Oncology Group · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a multi-centre, open label, phase 2, randomised controlled trial of patients with advanced triple negative breast cancer (TNBC) who have received no more than one line of chemotherapy (not including neoadjuvant or adjuvant therapy) who will be randomised to be treated with SABR 20Gy in 1# followed by atezolizumab or SABR 24Gy in 3# followed by atezolizumab.
Timeline
- Start
- 2018-08-01
- Primary completion
- 2023-06-22
- Completion
- 2023-06-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Atezolizumab | Monoclonal antibody | 1200 mg | — |