drugset / Trial / NCT03464942

Stereotactic Radiation and Immunotherapy in Patients With Advanced Triple Negative Breast Cancer

NCT03464942

RandomizedParallel-groupOpen-labelTreatment

Summary

This is a multi-centre, open label, phase 2, randomised controlled trial of patients with advanced triple negative breast cancer (TNBC) who have received no more than one line of chemotherapy (not including neoadjuvant or adjuvant therapy) who will be randomised to be treated with SABR 20Gy in 1# followed by atezolizumab or SABR 24Gy in 3# followed by atezolizumab.

Timeline

Start
2018-08-01
Primary completion
2023-06-22
Completion
2023-06-22

Drugs

EvaluationDrugModalityDoseRoute
Comparator Atezolizumab Monoclonal antibody 1200 mg

Indications