drugset / Trial / NCT03468010

A Trial Comparing Adjuvant Chemotherapy With Observation After Concurrent Chemoradiotherapy of Cervical Cancer (With Pelvic or Para-aortic Node Involvement)

NCT03468010 ↗

Phase 3 Unknown 432 enrolled Sun Yat-sen University
RandomizedParallel-groupOpen-labelTreatment

Summary

Cervical cancer with pelvic or para-aortic node involvement has a poor prognosis. Despite low-quality data, the routine practice to treat these patients is radiation with concurrent cisplatin. The aim of this study is to compare systemic chemotherapy with observation after radiation with concurrent cisplatin of cervical cancer ( with pelvic or para-aortic node involvement) for incidence of adverse events and local recurrence rate.

Timeline

Start
2018-03-01
Primary completion
2025-03-01
Completion
2025-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Cisplatin Other / unclassified 60 mg/m2 —
Subject Paclitaxel Small molecule 135 mg/m2 —