drugset / Trial / NCT03473210

The Value of Amniopatch in Preterm Premature Rupture of Membranes

NCT03473210

Completed 100 enrolled Cairo University
RandomizedParallel-groupOpen-labelTreatment

Summary

A randomized controlled trial that involved 100 women diagnosed with PPROM between 24 and 34 weeks of gestational age. Participants were randomized equally into 2 groups. Group I in which amniopatch was done (an amnioinfusion of platelet concentrate followed by fresh frozen plasma in addition to the routine management used in the control group. Group II were treated with routine management including antibiotics and corticosteroids

Timeline

Start
2016-10-01
Primary completion
2017-12-30
Completion
2018-03-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ampicillin Unknown 2 g Intravenous
Comparator Dexamethasone Small molecule 8 mg Intramuscular
Comparator Erythromycin Small molecule 250 mg