drugset / Trial / NCT03473210
The Value of Amniopatch in Preterm Premature Rupture of Membranes
RandomizedParallel-groupOpen-labelTreatment
Summary
A randomized controlled trial that involved 100 women diagnosed with PPROM between 24 and 34 weeks of gestational age. Participants were randomized equally into 2 groups. Group I in which amniopatch was done (an amnioinfusion of platelet concentrate followed by fresh frozen plasma in addition to the routine management used in the control group. Group II were treated with routine management including antibiotics and corticosteroids
Timeline
- Start
- 2016-10-01
- Primary completion
- 2017-12-30
- Completion
- 2018-03-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ampicillin | Unknown | 2 g | Intravenous |
| Comparator | Dexamethasone | Small molecule | 8 mg | Intramuscular |
| Comparator | Erythromycin | Small molecule | 250 mg | — |