drugset / Trial / NCT03474991
KIDS-STEP_Betamethasone Therapy in Hospitalised Children With CAP
Phase 3
Completed
510 enrolled
Julia Bielicki
Swiss National Fund for Scientific Research · collabSwissPedNet · collabUniversity Hospital, Basel, Switzerland · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to concurrently evaluate whether adjunct treatment with corticosteroids in children hospitalized with CAP is more effective in terms of the proportion of children reaching clinical stability and whether such adjunct treatment is no worse in terms of CAP relapse.
Timeline
- Start
- 2018-10-28
- Primary completion
- 2024-03-26
- Completion
- 2024-03-26
Publications
- Kohns Vasconcelos M, Meyer Sauteur PM, Keitel K, Santoro R, Heininger U, van den Anker J, Bielicki JA. Strikingly Decreased Community-acquired Pneumonia Admissions in Children Despite Open Schools and Day-care Facilities in Switzerland. Pediatr Infect Dis J. 2021 Apr 1;40(4):e171-e172. doi: 10.1097/INF.0000000000003026. No abstract available.
- Kohns Vasconcelos M, Meyer Sauteur PM, Santoro R, Coslovsky M, Lura M, Keitel K, Wachinger T, Beglinger S, Heininger U, van den Anker J, Bielicki JA. Randomised placebo-controlled multicentre effectiveness trial of adjunct betamethasone therapy in hospitalised children with community-acquired pneumonia: a trial protocol for the KIDS-STEP trial. BMJ Open. 2020 Dec 29;10(12):e041937. doi: 10.1136/bmjopen-2020-041937.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Betamethasone | Other / unclassified | 0.1 mg/kg | Oral |
| Comparator | Betamethasone | Other / unclassified | 0.2 mg/kg | Oral |