drugset / Trial / NCT03475160

Sildenafil Citrate and Recurrent Abortion

NCT03475160

Completed 130 enrolled Benha University
RandomizedParallel-groupDouble-blindTreatment

Summary

Two groups of unexplained recurrent spontaneous abortion, each included 65 participants. scheduled randomly into; the study group received Sildenafil Citrate and Placebo group. The intervention started from day 21-23 of the cycle preceding spontaneous pregnancy and continued till the 12th-week of gestation. The primary outcome measure was the difference in the live birth between both groups. Secondary outcome measures were the differences between both groups regard pulsatility index (PI) and resistance index (RI), a number of take-home babies, the reported side-effects of treatment and the pregnancy-related complications.

Timeline

Start
2015-12-01
Primary completion
2017-12-01
Completion
2017-12-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Sildenafil Unknown 25 mg Other