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drugset / Trial / NCT03476369

Fentanyl and Crushed Ticagrelor in Percutaneous Coronary Intervention

NCT03476369 ↗

Phase 4 Terminated 45 enrolled The Guthrie Clinic
RandomizedParallel-groupOpen-labelTreatment

Summary

During a percutaneous coronary intervention (PCI), Fentanyl is commonly used for sedation. Ticagrelor is also routinely used as anti-platelet agent during PCI. However, a recent study has demonstrated the decrease in effectiveness of Ticagrelor when administered along with Fentanyl. Hence this study was designed to further assess the interaction between crushed vs non crushed Ticagrelor and Fentanyl given during PCI procedures.

Timeline

Start
2018-04-18
Primary completion
2025-01-23
Completion
2025-01-23

Outcome

Outcome not reported

Stopped (Enrollment): “Researcher stopped study due to slow accrual rate”

Drugs

EvaluationDrugModalityDoseRoute
Subject Ticagrelor Small molecule 180 mg —
Background Fentanyl Other / unclassified 25 ug Intravenous

Indications

No indication recorded.