Infiltrations of OnaBotulinum Toxin A in Resistant Depression: Comparison of Two Facial Injection Sites.

Summary

The aim of the study is to evaluate in adult subjects with resistant depression the effect of an injection of botulinum toxin in the corrugator and procerus muscles, in comparison to the infiltration of the crow's feet area, in addition to the current antidepressant treatment.

Timeline

Start

2018-04-01

Primary completion

2021-07-30

Completion

2021-12-31

Publications

• Ceolato-Martin C, Chevallier-Collins C, Clement JP, Charles E, Lacroix A, Ranoux D. OnabotulinumtoxinA in Resistant Depression: A Randomized Trial Comparing Two Facial Injection Sites (OnaDEP Study). Depress Anxiety. 2024 Sep 12;2024:1177925. doi: 10.1155/2024/1177925. eCollection 2024.

Drugs

Indications