drugset / Trial / NCT03496870

A Study of the Pharmacokinetics, Pharmacodynamics, and Safety of Opicapone in Subjects With Parkinson's Disease Taking Levodopa.

NCT03496870

Phase 1 Completed 16 enrolled Neurocrine Biosciences
NaSingle-groupOpen-labelTreatment

Summary

This is a phase 1, open-label study to assess the pharmacokinetics, pharmacodynamics, safety, and tolerability of opicapone when administered orally once daily for 14 days as adjunctive therapy to carbidopa/levodopa in subjects with Parkinson's disease.

Timeline

Start
2018-02-08
Primary completion
2018-07-02
Completion
2018-07-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Levodopa Small molecule
Subject Opicapone Small molecule Oral
Background Carbidopa Unknown

Indications