drugset / Trial / NCT03497273
Safety of Itacitinib in Combination With Corticosteroids for Treatment of Steroid-Naive Acute Graft-Versus-Host Disease in Japanese Subjects
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to assess the safety and tolerability of itacitinib in combination with corticosteroids in Japanese subjects with Grades II to IV acute graft-versus-host disease (aGVHD).
Timeline
- Start
- 2018-03-20
- Primary completion
- 2019-11-30
- Completion
- 2020-02-17
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Itacitinib | Small molecule | — | Oral |
| Background | Methylprednisolone | Other / unclassified | — | Intravenous |
| Background | Prednisolone | Other / unclassified | — | Oral |