drugset / Trial / NCT03505489
The Effect of Deep Inhalation on Mannitol Responsiveness
RandomizedCrossoverOpen-labelOther
Summary
The study will assess how the inhalation technique used (deep inhalations versus tidal breathing) influences the results of a mannitol challenge test and a methacholine challenge test, if at all.
Timeline
- Start
- 2018-06-01
- Primary completion
- 2019-04-30
- Completion
- 2019-04-30
Publications
- Blais CM, Davis BE, Cockcroft DW. The effect of deep inhalation on mannitol responsiveness. Clin Exp Allergy. 2020 Mar;50(3):308-314. doi: 10.1111/cea.13543. Epub 2019 Dec 14.
- Blais CM, Davis BE, Graham BL, Cockcroft DW. Respiratory Duty Cycles in Individuals With and Without Airway Hyperresponsiveness. Chest. 2020 Feb;157(2):356-362. doi: 10.1016/j.chest.2019.09.005. Epub 2019 Sep 19.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Mannitol | Diagnostic / imaging agent | — | Inhaled |
| Subject | Methacholine | Diagnostic / imaging agent | — | Inhaled |