Block Duration After Spinal Block and iv Dexamethasone.

Phase 4 Completed 50 enrolled Eric Albrecht

RandomizedParallel-groupTriple-blindTreatment

Summary

It has been largely demonstrated that iv dexamethasone prolongs the duration of analgesia after peripheral nerve block. However, data are missing regarding the duration of analgesia after spinal block. The objective of this randomized controlled double-blinded trial is to assess whether intravenous dexamethasone administered after a spinal block, before the surgery would prolong sensory block characteristics without impacting the motor block duration.

Timeline

Start: 2018-05-01
Primary completion: 2021-11-01
Completion: 2022-04-01

Publications

Bikfalvi A, Hofmann G, Bashawyah A, Rossel JB, Gonvers E, Albrecht E. Sensory block duration after spinal anaesthesia supplemented with intravenous dexamethasone: a randomised controlled double-blinded trial. Br J Anaesth. 2023 Jun;130(6):780-785. doi: 10.1016/j.bja.2023.02.027. Epub 2023 Mar 23.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Dexamethasone	Small molecule	0.15 mg/kg	Intravenous

Indications

No indication recorded.