drugset / Trial / NCT03537287

Different Types of Progesterone in the Prevention of Preterm Labor

NCT03537287

Phase 2 Unknown 140 enrolled Ain Shams University
RandomizedParallel-groupOpen-labelPrevention

Summary

Preterm birth is a common problem in obstetric care,with estimates ranging from 5% in several European countries to 18% in some African countries, Preterm labor defined as delivery before 37 completed weeks is the leading cause of perinatal and neonatal morbidity and mortality and strongly related to the developmental and neurological disabilities later in life.. There is still considerable uncertainty regarding the optimal progesterone type, route of administration, dosage and timing of start of therapy to prevent preterm labor in risky women

Timeline

Start
2016-07
Primary completion
2018-07
Completion
2018-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator 17 alpha hydroxyprogestrone caproate Unknown 250 mg Intramuscular
Comparator Dydrogesterone Other / unclassified Oral
Comparator Progesterone Other / unclassified 200 mg Other

Indications

No indication recorded.