drugset / Trial / NCT03537287
Different Types of Progesterone in the Prevention of Preterm Labor
RandomizedParallel-groupOpen-labelPrevention
Summary
Preterm birth is a common problem in obstetric care,with estimates ranging from 5% in several European countries to 18% in some African countries, Preterm labor defined as delivery before 37 completed weeks is the leading cause of perinatal and neonatal morbidity and mortality and strongly related to the developmental and neurological disabilities later in life.. There is still considerable uncertainty regarding the optimal progesterone type, route of administration, dosage and timing of start of therapy to prevent preterm labor in risky women
Timeline
- Start
- 2016-07
- Primary completion
- 2018-07
- Completion
- 2018-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | 17 alpha hydroxyprogestrone caproate | Unknown | 250 mg | Intramuscular |
| Comparator | Dydrogesterone | Other / unclassified | — | Oral |
| Comparator | Progesterone | Other / unclassified | 200 mg | Other |
Indications
No indication recorded.