drugset / Trial / NCT03538314

UV1 Vaccine With Pembrolizumab for Patients With Unresectable or Metastatic Melanoma

NCT03538314

Phase 1 Completed 30 enrolled Ultimovacs ASA
NaSingle-groupOpen-labelTreatment

Summary

UV1 is a therapeutic cancer vaccine that has been explored in prostate and lung cancers, and in combination with ipilimumab in malignant melanoma. This study will explore the safety, tolerability and efficacy of UV1 administered with GM-CSF in melanoma patients who are also receiving pembrolizumab.

Timeline

Start
2018-07-09
Primary completion
2022-10-01
Completion
2024-06-15

Drugs

EvaluationDrugModalityDoseRoute
Subject UV1 Peptide 300 ug
Background sargramostim Protein / enzyme biologic 37.5 ug
Background sargramostim Protein / enzyme biologic 75 ug

Indications