drugset / Trial / NCT03541265

Liposomal Bupivacaine in Total Knee Arthroplasty

NCT03541265 ↗

RandomizedParallel-groupTriple-blindTreatment

Summary

Pain management after total knee arthroplasty is essential for optimized clinical outcomes and higher satisfaction. Exparel (Pacira Pharmaceuticals, Parsippany, New Jersey, USA) is a long-acting Bupivacaine extended release liposome compound that is injected peri-articularly or as regional block. The purpose of this study was to compare the analgesic efficacy of single administration of Exparel for local peri-articular infiltration versus adductor canal regional block.

Timeline

Start
2016-05-01
Primary completion
2017-06-01
Completion
2018-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupivacaine Other / unclassified 266 mg Other

Indications