drugset / Trial / NCT03553108
A Study Using Olaparib Tablets for Subjects With Advanced Solid Tumours.
RandomizedCrossoverOpen-labelTreatment
Summary
This is a phase 1 open label, 4 treatment, 4 sequence and 4 period crossover study in subjects with solid tumours no longer responding to, or eligible for standard therapies, and for whom there are no additional standard therapies likely to benefit the subject.
Timeline
- Start
- 2018-05-16
- Primary completion
- 2019-03-12
- Completion
- 2020-07-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Olaparib | Small molecule | 25 mg | — |
| Subject | Olaparib | Small molecule | 100 mg | — |
| Subject | Olaparib | Small molecule | 150 mg | — |
| Subject | Olaparib | Small molecule | 250 mg | — |