drugset / Trial / NCT03553498
IV Acetaminophen as Adjuvant Analgesic to Hydromorphone - Emergency Department Patients
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The goal of this randomized clinical trial is to compare the analgesic efficacy and side effect profile of IV acetaminophen as an analgesic adjunctive medication to IV hydromorphone for the treatment of acute pain experienced by patients in the Emergency Department (ED).
Timeline
- Start
- 2018-11-27
- Primary completion
- 2019-05-15
- Completion
- 2019-05-15
Outcome
Missed primary endpoint
registry analysis (superiority test); IV Hydromorphone and IV Acetaminophen vs IV Hydromorphone and Placebo; p = 0.08; t-test, 2 sided NCT03553498 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acetaminophen | Small molecule | 1000 mg | Intravenous |
| Background | Hydromorphone | Other / unclassified | 1 mg | Intravenous |
Indications
No indication recorded.