drugset / Trial / NCT03572959

Management of Pain in Oral Lichen Planus

NCT03572959

Phase 4 Completed 24 enrolled Sherine Adel Nasry
RandomizedParallel-groupTriple-blindSupportive care

Summary

Treating Oral Lichen Planus (OLP) is a big challenge for clinicians. Despite numerous existing remedies, to date no effective cure has been found, which is mainly attributed to the lack of understanding of the pathogenesis of the disease. The investigator's aim was comparing the effectiveness of topical steroids and diode laser in treating OLP patients. Twenty-four patients with OLP were allocated into two groups of twelve patients each. One group was treated with 970 nm diode laser applied twice weekly and the other group was treated with topical steroids applied four times per day. Patients were followed up for two months. Pain was recorded using the visual analog score (VAS) and the clinical signs and symptoms were recorded using the reticular, atrophic, erosive (RAE) sores. Pain and RAE records were taken before treatment, after treatment and after 2 months.

Timeline

Start
2016-12-27
Primary completion
2017-03-20
Completion
2017-05-22

Drugs

EvaluationDrugModalityDoseRoute
Comparator Triamcinolone Acetonide Other / unclassified 0.1 % Topical

Indications