drugset / Trial / NCT03584152

Postoperative Pain Management in Rhinoplasty

NCT03584152

Phase 2 Completed 159 enrolled Stanford University
RandomizedParallel-groupQuadruple-blindSupportive care

Summary

The primary purpose of the study is to determine adequacy of postoperative pain control after nasal surgery in patients prescribed Acetaminophen (325mg) + Hydrocodone (5mg) compared to Acetaminophen(325mg) + Ibuprofen (200mg)for a period of 5 days after nasal surgery. To assess the degree of pain, the participants will score the intensity of their pain on a visual analog scale(VAS)of 0-100points (0- no pain and 100- most severe pain), preoperatively and postoperatively (to be documented before each dose) for the duration of the prescribed medications . Additionally, the study will also seek to track: 1. The total number of pills each patients consume from the prescribed 5 day regimen. 2. Any associated side effects. 3. Additional pain medications prescribed in case of inadequate pain control, postoperatively.

Timeline

Start
2019-08-09
Primary completion
2024-11-14
Completion
2025-07-17

Drugs

EvaluationDrugModalityDoseRoute
Comparator Acetaminophen Small molecule 325 mg Oral
Comparator Hydrocodone Unknown 5 mg Oral
Comparator Ibuprofen Small molecule 200 mg Oral

Indications