drugset / Trial / NCT03585322
APG-1387 Study of Safety, Tolerability ,PK/PD in Patients With Chronic Hepatitis B
NaSingle-groupOpen-labelTreatment
Summary
This study is a Multiple Ascending Dose study to Explore the Tolerability, Safety and Pharmacokinetics/Pharmacodynamics of APG-1387 in Chronic Hepatitis B Patients.
Timeline
- Start
- 2018-07-04
- Primary completion
- 2021-10-15
- Completion
- 2021-10-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | APG-1387 | Small molecule | 7 mg | Intravenous |
| Subject | APG-1387 | Small molecule | 12 mg | Intravenous |
| Subject | APG-1387 | Small molecule | 20 mg | Intravenous |
| Subject | APG-1387 | Small molecule | 30 mg | Intravenous |
| Subject | APG-1387 | Small molecule | 45 mg | Intravenous |