drugset / Trial / NCT03599362

Study of Nivolumab, Cabiralizumab, and Stereotactic Body Radiotherapy (SBRT) for Locally Advanced Unresectable Pancreatic Cancer

NCT03599362

Phase 2 Terminated 7 enrolled NYU Langone Health
NaSingle-groupOpen-labelTreatment

Summary

A multi-institutional, single arm phase II study of nivolumab, cabiralizumab and stereotactic body radiotherapy (SBRT) in patients with LAUPC. The purpose of this study is to determine the safety and tolerability of combined cabiralizumab, nivolumab and radiotherapy in the treatment of locally advanced pancreatic cancer. Investigators will also estimate the surgical resection rate following treatment with combined cabiralizumab, nivolumab and radiotherapy in subjects with locally advanced unresectable pancreatic cancer.

Timeline

Start
2018-07-31
Primary completion
2020-06-15
Completion
2020-06-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Cabiralizumab Monoclonal antibody
Subject Nivolumab Monoclonal antibody