drugset / Trial / NCT03600870

Midodrine in Hepatopulmonary Syndrome

NCT03600870

Phase 1 Completed 10 enrolled Mayo Clinic
NaSingle-groupOpen-labelTreatment

Summary

This proof-of-concept clinical trial will determine the safety and tolerability of midodrine in patients with hepatopulmonary syndrome (HPS). Exploratory endpoints will assess the effect of midodrine on oxygenation, intrapulmonary shunting and symptoms.

Timeline

Start
2018-08-02
Primary completion
2020-12-01
Completion
2020-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Midodrine Small molecule 10 mg Oral