Phase 1 7 trials
Phase 1
NCT03600870 Aug 2018 → Dec 2020 hepatopulmonary syndrome Mayo Clinic
Completed
No outcome recorded
Phase 1
NCT02897063 Sep 2016 → Sep 2026 overdue Parkinson disease , orthostatic hypotension , pure autonomic failure Vanderbilt University Medical Center
Recruiting
No outcome recorded
Phase 1
NCT02429557 Apr 2015 → Dec 2025 orthostatic hypotension , pure autonomic failure Vanderbilt University Medical Center
Completed
No outcome recorded
Phase 1
NCT00648440 Oct → Nov 2002 —
Mylan Pharmaceuticals Inc
Completed
No outcome recorded
Phase 1
NCT00650364 Aug 2002 —
Mylan Pharmaceuticals Inc
Completed
No outcome recorded
Phase 1
NCT00650013 Jul → Aug 2002 —
Mylan Pharmaceuticals Inc
Completed
No outcome recorded
Phase 1
NCT00223691 Mar 2002 → Jan 2017 autonomic nervous system disorder , orthostatic hypotension Vanderbilt University
Completed
Mixed
Phase 1/2 2 trials · 1 missed
Phase 1/2
NCT03482297 Mar 2018 → Nov 2025 orthostatic hypotension , pure autonomic failure Vanderbilt University Medical Center
Completed
No outcome recorded
Phase 1/2
NCT00262470 Apr 1997 → Dec 2029 expected cardiac rhythm disease Satish R. Raj
Active not recruiting
Missed primary
Phase 2 10 trials
Phase 2
NCT06319248 May 2024 → May 2029 expected hypotensive disorder , infectious disease with sepsis Mayo Clinic
Recruiting
No outcome recorded
Phase 2
NCT04586790 Oct 2020 → Jan 2021 —
Ahmed talaat ahmed aly
Unknown
No outcome recorded
Phase 2
NCT02893553 Dec 2016 → Dec 2021 autonomic dysreflexia , cognitive disorder , hypotensive disorder , spinal cord injury James J. Peters Veterans Affairs Medical Center
Completed
No outcome recorded
Phase 2
NCT01587222 Jul 2016 → Jul 2017 hepatorenal syndrome , kidney failure Anna Cruceta
Withdrawn
No outcome recorded
Phase 2
NCT01546506 Feb 2012 → Mar 2014 influenza Hospices Civils de Lyon
Completed
No outcome recorded
Phase 2
NCT00835224 May 2010 → Jun 2013 orthostatic hypotension , spinal cord injury US Department of Veterans Affairs
Completed
No outcome recorded
Phase 2
NCT01133795 Feb 2010 → Jun 2016 cirrhosis of liver , kidney failure Hospital Clinic of Barcelona
Completed
No outcome recorded
Phase 2
NCT00426842 Jan 2007 → Mar 2011 orthostatic hypotension , spinal cord injury James J. Peters Veterans Affairs Medical Center
Completed
No outcome recorded
Phase 2
NCT00227448 Jun 2003 → Apr 2005 ischemic stroke Johns Hopkins University
Completed
No outcome recorded
Phase 2
NCT00004268 Apr 2001 → ? orthostatic hypotension National Center for Research Resources (NCRR)
Completed
No outcome recorded
Phase 2/3 5 trials · 1 missed
Phase 2/3
NCT06405555 Aug 2026 → Jun 2028 expected hypotensive disorder , left ventricular failure , symptomatic heart failure Ottawa Heart Institute Research Corporation
Recruiting
No outcome recorded
Phase 2/3
NCT02919917 Jun 2017 → Sep 2021 autonomic dysreflexia , orthostatic hypotension , spinal cord injury James J. Peters Veterans Affairs Medical Center
Completed
Missed primary
Phase 2/3
NCT02173288 Jul 2013 → Mar 2016 cirrhosis of liver Post Graduate Institute of Medical Education and Research, Chandigarh
Completed
No outcome recorded
Phase 2/3
NCT00240045 Oct 2005 → Jul 2007 hepatorenal syndrome University of Alberta
Completed
No outcome recorded
Phase 2/3
NCT00742339 May 2005 → Oct 2013 cirrhosis of liver , hepatorenal syndrome University of Padova
Terminated
No outcome recorded
Phase 3 5 trials
Phase 3
NCT05240391 Feb 2021 → May 2022 —
Asian Institute of Gastroenterology, India
Completed
No outcome recorded
Phase 3
NCT03706053 Nov 2018 → Feb 2022 infectious disease with sepsis University of Virginia
Terminated
No outcome recorded
Stop: Business
Phase 3
NCT02990546 Mar 2017 → May 2018 infectious disease with sepsis University of Virginia
Withdrawn
No outcome recorded
Stop: Enrollment
Phase 3
NCT02307565 Mar 2014 → Dec 2019 spinal cord injury James J. Peters Veterans Affairs Medical Center
Completed
No outcome recorded
Phase 3
NCT01707953 Oct 2012 → Sep 2013 orthostatic hypotension Rigshospitalet, Denmark
Completed
No outcome recorded
Phase 4 13 trials · 1 met primary · 1 missed
Phase 4
NCT05839652 Jul 2023 → Jun 2026 overdue hypotensive disorder James J. Peters Veterans Affairs Medical Center
Recruiting
No outcome recorded
Phase 4
NCT04489589 Mar 2021 → Jul 2022 —
University of Alberta
Completed
No outcome recorded
Phase 4
NCT05058612 Mar 2021 → Mar 2027 expected vascular disorder University of Alberta
Recruiting
No outcome recorded
Phase 4
NCT02771158 Aug → Nov 2017 hypotensive disorder , infectious disease with sepsis Northwell Health
Withdrawn
No outcome recorded
Phase 4
NCT03080441 Nov 2016 → Apr 2017 —
Nimedical
Unknown
No outcome recorded
Phase 4
NCT02379156 Apr 2015 → Jul 2021 cognitive impairment with or without cerebellar ataxia , quadriplegia James J. Peters Veterans Affairs Medical Center
Completed
Met primary
Phase 4
NCT02308124 Nov 2014 → Sep 2016 orthostatic hypotension Seoul National University Hospital
Completed
No outcome recorded
Phase 4
NCT01515865 May 2012 → Nov 2013 orthostatic hypotension Shire
Completed
Missed primary
Phase 4
NCT01822535 Jul 2011 → Oct 2015 cognitive impairment with or without cerebellar ataxia , quadriplegia James J. Peters Veterans Affairs Medical Center
Completed
Mixed
Phase 4
NCT00555880 Sep 2004 → Mar 2005 orthostatic hypotension Shire
Completed
Mixed
Phase 4
NCT00108355 Dec 2003 → Aug 2010 cirrhosis of liver US Department of Veterans Affairs
Completed
No outcome recorded
Phase 4
NCT00046163 Sep 2002 → Aug 2003 orthostatic hypotension Shire
Terminated
No outcome recorded
Stop: Enrollment
Phase 4
NCT00046475 Dec 1997 → Nov 1999 orthostatic hypotension Shire
Completed
Mixed
Show 3 more trials Phase not applicable 17 trials
— NCT07465471 Mar 2026 → Sep 2027 expected cirrhosis of liver Institute of Liver and Biliary Sciences, India
Not yet recruiting
No outcome recorded
— NCT07422948 Feb 2026 → Aug 2027 expected liver failure Institute of Liver and Biliary Sciences, India
Not yet recruiting
No outcome recorded
— NCT06245590 Feb 2024 → Jan 2025 cirrhosis of liver Institute of Liver and Biliary Sciences, India
Unknown
No outcome recorded
— NCT05287100 Jan 2022 → May 2023 cirrhosis of liver Institute of Liver and Biliary Sciences, India
Completed
No outcome recorded
— NCT05084534 Nov 2021 → Feb 2023 —
Institute of Liver and Biliary Sciences, India
Withdrawn
No outcome recorded
— NCT05060523 Sep 2021 → Sep 2022 cirrhosis of liver Institute of Liver and Biliary Sciences, India
Unknown
No outcome recorded
— NCT04881318 May 2021 → Dec 2026 expected postural orthostatic tachycardia syndrome University of Calgary
Recruiting
No outcome recorded
— NCT04816240 May 2021 → Mar 2022 cirrhosis of liver Institute of Liver and Biliary Sciences, India
Unknown
No outcome recorded
— NCT04474262 Jul 2020 → Mar 2021 liver disorder Institute of Liver and Biliary Sciences, India
Unknown
No outcome recorded
— NCT04455464 Jul 2020 → Dec 2021 liver disorder Institute of Liver and Biliary Sciences, India
Completed
No outcome recorded
— NCT04043858 Jun 2020 → Jun 2021 —
National Liver Institute, Egypt
Unknown
No outcome recorded
— NCT04208776 Feb 2020 → Dec 2021 cirrhosis of liver Institute of Liver and Biliary Sciences, India
Completed
No outcome recorded
— NCT03645642 Sep → Dec 2018 hepatobiliary disorder Institute of Liver and Biliary Sciences, India
Completed
No outcome recorded
— NCT04522297 Apr 2018 → Jan 2020 hepatorenal syndrome National Hepatology & Tropical Medicine Research Institute
Completed
No outcome recorded
— NCT02154243 Jun 2014 → Jan 2015 orthostatic hypotension Hospital for Special Surgery, New York
Terminated
No outcome recorded
— NCT01331785 Apr 2011 → Jul 2012 chronic liver failure , cirrhosis of liver , hypotensive disorder The Cleveland Clinic
Withdrawn
No outcome recorded
Stop: Enrollment
— NCT00004479 Mar 1999 → ? —
Icahn School of Medicine at Mount Sinai
Completed
No outcome recorded
Show 7 more trials Comparator or background therapy 27 trials
Phase 0
NCT04620382 Comparator Nov 2020 → Jul 2025 Parkinson disease , orthostatic hypotension , pure autonomic failure Vanderbilt University Medical Center
Completed
No outcome recorded
Phase 1
NCT03129542 Comparator Aug 2017 → Apr 2020 infectious disease with sepsis Mayo Clinic
Completed
No outcome recorded
Phase 1/2
NCT07432997 Comparator Dec 2023 → Sep 2024 Alzheimer disease Applied Cognition
Completed
No outcome recorded
Phase 2
NCT05778838 Comparator Nov 2022 → Dec 2023 infectious disease with sepsis Noha Mansour
Completed
No outcome recorded
Phase 2
NCT04048707 Comparator Jul 2021 → Jun 2023 acute kidney injury , cirrhosis of liver , hepatorenal syndrome University of California, Los Angeles
Withdrawn
No outcome recorded
Stop: Business
Phase 3
NCT04595942 Comparator Nov 2020 → Oct 2023 syncope, familial vasovagal Tehran Heart Center
Unknown
No outcome recorded
Phase 3
NCT04621617 Comparator Nov 2020 → Dec 2021 —
Post Graduate Institute of Medical Education and Research, Chandigarh
Unknown
No outcome recorded
Phase 3
NCT01531959 Comparator Apr 2012 → Jun 2019 hypotensive disorder Massachusetts General Hospital
Completed
No outcome recorded
Phase 4
NCT04440085 Comparator Sep 2020 orthostatic hypotension Bürgerspital Solothurn
Unknown
No outcome recorded
Phase 4
NCT03455322 Comparator Aug 2018 → Apr 2020 hepatorenal syndrome National Hepatology & Tropical Medicine Research Institute
Completed
No outcome recorded
Phase 4
NCT03350659 Comparator Jan 2018 → Jan 2019 orthostatic hypotension Seoul National University Hospital
Completed
No outcome recorded
Phase 4
NCT03911817 Comparator Nov 2017 → Jun 2019 infectious disease with sepsis Ain Shams University
Completed
No outcome recorded
Phase 4
NCT04668859 Comparator Jul 2016 → Aug 2018 isoproterenol-mediated vasodilatation Medstar Health Research Institute
Terminated
No outcome recorded
Phase 4
NCT01518946 Comparator May 2012 → Jun 2013 orthostatic hypotension Shire
Completed
No outcome recorded
Phase 4
NCT01456481 Comparator Nov 2011 → Dec 2018 syncope, familial vasovagal Dr. Bob Sheldon
Unknown
No outcome recorded
Phase 4
NCT00839358 Comparator Aug 2008 → Feb 2016 hepatic encephalopathy , infectious disease with sepsis , kidney failure Hospital Clinic of Barcelona
Completed
No outcome recorded
— NCT06930235 Comparator Mar → Oct 2025 —
Sohag University
Completed
No outcome recorded
— NCT06213935 Comparator Feb → Oct 2024 —
Sohag University
Unknown
No outcome recorded
— NCT06091345 Background Dec 2023 → Dec 2025 cirrhosis of liver Institute of Liver and Biliary Sciences, India
Completed
No outcome recorded
— NCT05803148 Comparator Apr 2023 → Dec 2024 syncope, familial vasovagal China National Center for Cardiovascular Diseases
Unknown
No outcome recorded
— NCT05548985 Comparator Oct 2022 → Jul 2023 hypotensive disorder Cairo University
Completed
No outcome recorded
— NCT04782830 Comparator Feb 2021 → Jun 2027 expected orthostatic hypotension , pure autonomic failure Vanderbilt University Medical Center
Recruiting
No outcome recorded
— NCT04396548 Comparator Jun → Dec 2020 —
Mansoura University
Completed
No outcome recorded
— NCT03144713 Comparator May 2017 → Apr 2018 cirrhosis of liver Institute of Liver and Biliary Sciences, India
Completed
No outcome recorded
— NCT03431194 Comparator Oct 2016 → Feb 2017 acute kidney injury Benha University
Completed
No outcome recorded
— NCT02123576 Background Apr 2014 → Dec 2017 hepatorenal syndrome Patrick Northup, MD
Terminated
No outcome recorded
Stop: Enrollment
— NCT02365012 Comparator Apr 2014 → Jun 2017 Parkinson disease Corporal Michael J. Crescenz VA Medical Center
Unknown
No outcome recorded
Show 22 more trials