Nor-epinephrine Versus Midodrine/Octreotide in Patients With Hepatorenal Syndrome

Summary

Hepatorenal syndrome is a functional renal impairment occurring in cirrhotic patients . It develops secondary to splanchnic arterial vasodilatation which decreases the effective blood volume, activate the renin-angiotensin-aldosterone system, and stimulate of sympathetic nervous system.This study aims to compare the efficacy of nor-epinephrine versus midodrine/ octreotide, together with intravenous albumin on renal functions of patients with hepatorenal acute kidney injury.

Timeline

Start

2018-04-15

Primary completion

2020-01-23

Completion

2020-01-23

Drugs

Indications