Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure

Summary

The purpose of this study is to learn more about the effects of midodrine and droxidopa, two medications used for the treatment of orthostatic hypotension (low blood pressure on standing), on the veins of the abdomen of patients with autonomic failure. The study will be conducted at Vanderbilt University Medical Center, and consists of 2 parts: a screening and 2 testing days. The total length of the study will be about 5 days. About 34 participants will be screened for the study.

Timeline

Start

2016-09

Primary completion

2026-09

Completion

2026-12

Drugs

Indications