drugset / Trial / NCT00227448
Induced Hypertension for Acute Ischemic Stroke
Non-randomizedSingle-groupOpen-labelTreatment
Summary
The ultimate goal of this multicenter, phase II study is to increase blood pressure until either a neurologic response is seen or a target mean arterial pressure of 30% above baseline is achieved. IV fluids, IV phenylephrine and/or IV norepinephrine are used to rapidly raise mean arterial pressure in a controlled manner as serial assessments of neurologic function are performed.
Timeline
- Start
- 2003-06
- Primary completion
- —
- Completion
- 2005-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Midodrine | Small molecule | — | Oral |
| Subject | Phenylephrine | Small molecule | — | Intravenous |
| Subject | levophed | Unknown | — | Intravenous |