drugset / Trial / NCT00227448

Induced Hypertension for Acute Ischemic Stroke

NCT00227448

Non-randomizedSingle-groupOpen-labelTreatment

Summary

The ultimate goal of this multicenter, phase II study is to increase blood pressure until either a neurologic response is seen or a target mean arterial pressure of 30% above baseline is achieved. IV fluids, IV phenylephrine and/or IV norepinephrine are used to rapidly raise mean arterial pressure in a controlled manner as serial assessments of neurologic function are performed.

Timeline

Start
2003-06
Primary completion
Completion
2005-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Midodrine Small molecule Oral
Subject Phenylephrine Small molecule Intravenous
Subject levophed Unknown Intravenous

Indications