Midodrine Effect on the Mortality Rates in Septic Shock Patients

Summary

Assessing the safety and efficacy of the adjunctive use of midodrine as a vasopressor in septic shock patients by measuring the difference in the mortality rates between control and intervention groups.

Timeline

Start

2022-11-07

Primary completion

2023-12-22

Completion

2024-01-24

Publications

• El-Nagdy NK, Mansour NO, Diab AAA, Soliman MM. Efficacy of adjuvant use of midodrine in patients with septic shock: An open label randomized controlled trial. Pharmacotherapy. 2025 May;45(5):264-272. doi: 10.1002/phar.70018. Epub 2025 Apr 16.

Drugs

Indications