drugset / Trial / NCT03601897

A Phase 1b/2 Study of Rebastinib (DCC-2036) in Combination With Paclitaxel in Patients With Advanced or Metastatic Solid Tumors

NCT03601897

Phase 1/2 Terminated 177 enrolled Deciphera Pharmaceuticals, LLC
Non-randomizedSequentialOpen-labelTreatment

Summary

This is an open-label Phase 1b/2 multicenter study of rebastinib (DCC-2036) in combination with paclitaxel designed to evaluate the safety, tolerability, and pharmacokinetics (PK) in patients with advanced or metastatic solid tumors.

Timeline

Start
2018-10-25
Primary completion
2022-05-23
Completion
2022-05-23

Drugs

EvaluationDrugModalityDoseRoute
Subject Paclitaxel Small molecule 80 mg/m2 Intravenous
Subject Rebastinib Small molecule 50 mg Oral
Subject Rebastinib Small molecule 100 mg Oral

Indications

No indication recorded.