Trimetazidine as an Adjunct to Enhance Clopidogrel Response.

Summary

Hypothesis: Trimetazidine improves Clopidogrel response in patients. • The investigators postulate that the inhibition of platelet aggregation in response to Clopidogrel may be accentuated by Trimetazidine, i.e. Trimetazidine enhances Clopidogrel response. Null Hypothesis: There is no difference in Clopidogrel response in patients with stable coronary artery disease with adjunctive Trimetazidine.

Timeline

Start

2018-07-01

Primary completion

2019-04-01

Completion

2019-04-01

Publications

• Seecheran N, Seebalack V, Seecheran R, Maharaj A, Boodhai B, Seecheran V, Persad S, Motilal S, Tello-Montoliu A, Schneider D. TRimetazidine as an Agent to affeCt clopidogrEl Response: The TRACER Study. Cardiol Ther. 2019;8(2):229-237. doi: 10.1007/s40119-019-0139-0. Epub 2019 Jul 10.

Drugs

Indications