drugset / Trial / NCT03620760

Efficacy and Safety of Low Dose Ticagrelor in Patients With Unstable Angina Pectoris After Coronary Stent Implantation

NCT03620760

Phase 4 Unknown 2036 enrolled Xiaofan Wu
RandomizedParallel-groupOpen-labelTreatment

Summary

The study is to evaluate efficacy and safety of low dose of ticagrelor therapy for Chinese unstable angina patients treated with non-urgent coronary stent implantation, to examine whether lower dose ticagrelor (45 mg twice-daily) is not inferior to standard dose (90 mg twice-daily) for the prevention of major adverse cardiovascular and cerebrovascular events, as well as will reduce the incidence of bleeding during long-term treatment.

Timeline

Start
2018-08-07
Primary completion
2020-12-31
Completion
2020-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ticagrelor Small molecule 45 mg
Comparator Ticagrelor Small molecule 90 mg
Background Aspirin Small molecule 100 mg