drugset / Trial / NCT03620760
Efficacy and Safety of Low Dose Ticagrelor in Patients With Unstable Angina Pectoris After Coronary Stent Implantation
RandomizedParallel-groupOpen-labelTreatment
Summary
The study is to evaluate efficacy and safety of low dose of ticagrelor therapy for Chinese unstable angina patients treated with non-urgent coronary stent implantation, to examine whether lower dose ticagrelor (45 mg twice-daily) is not inferior to standard dose (90 mg twice-daily) for the prevention of major adverse cardiovascular and cerebrovascular events, as well as will reduce the incidence of bleeding during long-term treatment.
Timeline
- Start
- 2018-08-07
- Primary completion
- 2020-12-31
- Completion
- 2020-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ticagrelor | Small molecule | 45 mg | — |
| Comparator | Ticagrelor | Small molecule | 90 mg | — |
| Background | Aspirin | Small molecule | 100 mg | — |