drugset / Trial / NCT03631433

Ibuprofen Versus Ibuprofen/Acetaminophen Postoperatively in Patients Needing Root Canal Therapy

NCT03631433 ↗

Phase 4 Completed 102 enrolled Ohio State University
RandomizedParallel-groupTriple-blindTreatment

Summary

Aim: The purpose of this study was to compare ibuprofen versus an ibuprofen/acetaminophen combination for postoperative pain control in patients requiring root canal treatment with a tooth that is painful to cold and biting. Methodology: Following regular root canal treatment, patients randomly received identical appearing tablets of 600 mg ibuprofen or 600 mg ibuprofen/650 mg acetaminophen to be taken every 6 hours as needed for pain. A 4-day diary was used to record pain and medication use.

Timeline

Start
2016-02-10
Primary completion
2017-05-01
Completion
2017-07-17

Drugs

EvaluationDrugModalityDoseRoute
Subject Acetaminophen Small molecule 650 mg —
Comparator Ibuprofen Small molecule 600 mg —

Indications