drugset / Trial / NCT03631641

Nivolumab in Preventing Colon Adenomas in Participants With Lynch Syndrome and a History of Partial Colectomy

NCT03631641 ↗

Phase 2 Terminated 3 enrolled John Hays Bristol-Myers Squibb · collab
NaSingle-groupOpen-labelPrevention

Summary

This phase II trial studies how well nivolumab works in preventing colon adenomas in participants with Lynch syndrome and a history of surgery to remove part of the colon. Monoclonal antibodies, such as nivolumab, may interfere with the ability of tumor cells to grow and spread.

Timeline

Start
2018-10-04
Primary completion
2021-01-25
Completion
2021-01-25

Outcome

Outcome not reported

Stopped (Business): “Sponsor decision”

Drugs

EvaluationDrugModalityDoseRoute
Subject Nivolumab Monoclonal antibody — Intravenous