drugset / Trial / NCT03644823

Combinatory ImmunoTherapy-1 (Com-IT-1) Irradiation and PD-1 Blockade in Locally Advanced / Advanced NSCLC

NCT03644823 ↗

Phase 2 Terminated 21 enrolled Oslo University Hospital
NaSingle-groupOpen-labelTreatment

Summary

In this study, the investigators will investigate toxicity in patients treated with a Programmed cell death protein 1 (PD-1) inhibitor and radiotherapy. Patients with advanced Non-Small Cell Lung Cancer (NSCLC) can be included when treatment with a PD-1 inhibitor is indicated according to national guidelines. Included patients will receive stereotactic radiotherapy to one or two tumour lesion(s) in addition to the PD-1 inhibitor, and toxicity is the primary endpoint.

Timeline

Start
2018-08-15
Primary completion
2020-12-31
Completion
2020-12-31

Outcome

Outcome not reported

Stopped (Enrollment): “slow recruiting”

Drugs

EvaluationDrugModalityDoseRoute
Subject Atezolizumab Monoclonal antibody — —