drugset / Trial / NCT03648008
Postoperative Analgesic Effect of Hydromorphone on Partial Pulmonary Resection Under Video-assisted Thoracoscopy
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Postoperative pain remains relatively high within 48h for Chinese patients who receive video-assisted thoracoscopic surgery. Multimodal analgesia combines several agents and/or techniques to function on diverse nociceptive mechanisms to enhance pain relief and lessen side effect. Hydromorphone is a hydrogenated ketone of morphine and approximately 5-10 times more potent. There lacks about efficacy and efficiency of hydromorphone in electrical pump for patient controlled intravenous analgesic (PCIA).
Timeline
- Start
- 2018-05-05
- Primary completion
- 2018-09-01
- Completion
- 2018-09-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Hydromorphone | Other / unclassified | 0.002 mg/kg | Intravenous |
| Comparator | Morphine | Other / unclassified | 0.015 mg/kg | Intravenous |