drugset / Trial / NCT03648008

Postoperative Analgesic Effect of Hydromorphone on Partial Pulmonary Resection Under Video-assisted Thoracoscopy

NCT03648008

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Postoperative pain remains relatively high within 48h for Chinese patients who receive video-assisted thoracoscopic surgery. Multimodal analgesia combines several agents and/or techniques to function on diverse nociceptive mechanisms to enhance pain relief and lessen side effect. Hydromorphone is a hydrogenated ketone of morphine and approximately 5-10 times more potent. There lacks about efficacy and efficiency of hydromorphone in electrical pump for patient controlled intravenous analgesic (PCIA).

Timeline

Start
2018-05-05
Primary completion
2018-09-01
Completion
2018-09-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Hydromorphone Other / unclassified 0.002 mg/kg Intravenous
Comparator Morphine Other / unclassified 0.015 mg/kg Intravenous

Indications