drugset / Trial / NCT03649659
Effectiveness of Silver Diamine Fluoride (SDF) in Arresting Cavitated Caries Lesions
Phase 3
Terminated
830 enrolled
University of Michigan
NYU Langone Health · collabNational Institute of Dental and Craniofacial Research (NIDCR) · collabUniversity of Iowa · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This trial is a Phase III, multisite, randomized, placebo-controlled trial, with two parallel groups. The groups are SDF or placebo and they are applied every 6 months. The primary hypothesis of the trial is that SDF is better than placebo for stopping cavities with dentin exposed in baby teeth when assessed at 6 months after initial application.
Timeline
- Start
- 2018-10-08
- Primary completion
- 2023-04-11
- Completion
- 2023-04-27
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | silver diammine fluoride | Small molecule | — | Topical |
Indications
No indication recorded.