drugset / Trial / NCT03658057

Measurement of the Skin Sympathetic Nerve Activity

NCT03658057

Completed 20 enrolled Seoul National University Hospital
RandomizedParallel-groupQuadruple-blindOther

Summary

Sympathetic nerve activity can be measured transcutaneously in awake patients by computer-based filtering of raw signal obtained via skin leads attached on the chest. Electrocardiogram can be removed by applying a high-pass filter setting of 150 Hz. Electromyogram can be filtered by applying a high-pass filter setting of 500 Hz or a band-pass filter setting of 500-1000 Hz. However, it is not known whether the skin sympathetic nerve activity (SKNA) can be measured in anesthetized and/or paralyzed patients. Therefore, we planned this pilot study to observe whether the SKNA can be obtained in these patients. If the SKNA ca be observed, it will be presented in milivolt (uV).

Timeline

Start
2018-08-31
Primary completion
2018-11-01
Completion
2018-11-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Rocuronium Other / unclassified 0.4 mg/kg
Comparator Rocuronium Other / unclassified 0.8 mg/kg

Indications

No indication recorded.