drugset / Trial / NCT03660930

Nab-Sirolimus and Pazopanib Hydrochloride in Treating Patients With Advanced Nonadipocytic Soft Tissue Sarcomas

NCT03660930

NaSingle-groupOpen-labelTreatment

Summary

This phase I/II trial studies the side effects and best dose of nab-sirolimus and how well it works when given together with pazopanib hydrochloride in treating participants with nonadipocytic soft tissue sarcomas that has spread to other places in the body (advanced). Nab-sirolimus and pazopanib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2019-04-01
Primary completion
2022-11-17
Completion
2024-07-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Pazopanib Small molecule Oral
Subject Sirolimus Small molecule Intravenous

Indications