drugset / Trial / NCT03664830

Safety of Blood Stem Cell Mobilization With Plerixafor in Patients With Sickle Cell Disease

NCT03664830

Phase 1 Active not recruiting 5 enrolled City of Hope Medical Center
NaSingle-groupOpen-labelTreatment

Summary

The objective of this study is to investigate if up to two injections of plerixafor represent a safe and effective strategy to mobilize adequate numbers of CD34+ hematopoietic stem progenitor cells (HSPC) for autologous hematopoietic cell transplantation (HCT) in sickle cell disease (SCD) patients

Timeline

Start
2018-09-19
Primary completion
2026-08-03
Completion
2026-08-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Plerixafor Small molecule 240 ug/kg Subcutaneous

Indications