drugset / Trial / NCT03670056

Ipilimumab and Nivolumab in Recurrent Extensive Stage Small Cell Lung Cancer After Receiving Platinum-based Chemotherapy

NCT03670056 ↗

Phase 2 Active not recruiting 25 enrolled Yale University Bristol-Myers Squibb · collab
NaSingle-groupOpen-labelTreatment

Summary

This is a pilot study of patients who previously received platinum chemotherapy with recurrent SCLC to evaluate the change in the ratio of intratumoral Teff/Treg cells and clinical benefit of treatment with nivolumab and ipilimumab.

Timeline

Start
2018-12-06
Primary completion
2025-12
Completion
2025-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Ipilimumab Monoclonal antibody 3 mg/kg —
Subject Nivolumab Monoclonal antibody 240 mg —