drugset / Trial / NCT03671538

Non Squamous NSCLC Patients With Anlotinib Combined With Pemetrexed and Cisplatin

NCT03671538

Unknown 62 enrolled Lingyu Luo
NaSingle-groupOpen-labelTreatment

Summary

Chemotherapy is still the standard first-line treatment option for EGFR unmutated patients. After a randomized phase Ⅲ trial, BEYOND was presented the synergistic effect of progression-free survival(PFS) could be expected when chemotherapy is combined with Antiangiogenesis agent bevacizumab in China;Therefore,in this study, The investigators will investigate the efficacy and safety of Anlotinb combined With Pemetrexed and Cisplatin as first-line therapy in patients with chemotherapy-naive, stage IIIB or IV, non-squamous NSCLC without targetable EGFR or ALK genetic aberrations.

Timeline

Start
2018-10-01
Primary completion
2019-08-31
Completion
2020-08-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Catequentinib Small molecule 12 mg Oral
Subject Cisplatin Other / unclassified 75 mg/m2
Subject Pemetrexed Small molecule 500 mg/m2 Intravenous