drugset / Trial / NCT03671538
Non Squamous NSCLC Patients With Anlotinib Combined With Pemetrexed and Cisplatin
NaSingle-groupOpen-labelTreatment
Summary
Chemotherapy is still the standard first-line treatment option for EGFR unmutated patients. After a randomized phase Ⅲ trial, BEYOND was presented the synergistic effect of progression-free survival(PFS) could be expected when chemotherapy is combined with Antiangiogenesis agent bevacizumab in China;Therefore,in this study, The investigators will investigate the efficacy and safety of Anlotinb combined With Pemetrexed and Cisplatin as first-line therapy in patients with chemotherapy-naive, stage IIIB or IV, non-squamous NSCLC without targetable EGFR or ALK genetic aberrations.
Timeline
- Start
- 2018-10-01
- Primary completion
- 2019-08-31
- Completion
- 2020-08-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Catequentinib | Small molecule | 12 mg | Oral |
| Subject | Cisplatin | Other / unclassified | 75 mg/m2 | — |
| Subject | Pemetrexed | Small molecule | 500 mg/m2 | Intravenous |